ANTIPSORIATIKUM (Antipsoriaticum).

     Ointments containing 0,001 or 0,0025 trihlortrietilamina g per 100 g medical vaseline (1:40000 or 1:100 000), white or yellow.

     Trihlortrietilamin (nitrogen mustard) is classified kozhnonaryvnogo action. When the skin causing it to irritating effect, and can cause destruction varying from mild erythema before the bubble and then pitting and necrotic tissue (depending on the concentration, duration of exposure, individual sensitivity, etc.). Heavy defeats are by ingestion trihlortrietilamina on mucous membranes (especially the eye). The local action by obscherezorbtivnymi toxic phenomena.

     In very large breeding (1:100 00-1 : 40000) trihlortrietilamin proposed for the treatment of psoriasis. Mechanism of action is not clear. Can play a role irritating effect on the skin receptors, as well as interaction with proteins in the skin and the impact enzyme system.

     Applied ointment "Antipsoriatikum" in all forms of eczema (in the stationary phase), and sometimes also in gnezdnom serve.

     Assign External preparation. Started with cautious causing masi concentration 1:100 000 in the limited areas affected 1 to 2 times a day for 2 to 3 days. In case of hypersensitivity skin preparation overturned. With good endurance cuticles all stung the skin 2 times a day. The first 5 to 6 days ointment place without casts, a 7-day suspension doing, the patient takes a bath and change of clothes. For the 2 nd week with good endurance cuticles stung the skin ointment (or lightly rubbing her), and placed a wax-lined paper, fixing her bandages in the first 2 - 3 days to 1 to 2 h, in the next-to 2 - 4 hours After 2 weeks of the start of treatment makes a break for 3 to 5 days, then resume treatment. During this period designate 1 - 2% salitsilovuyu ointment.

     Ointments rubbing in the direction of hair growth (except perhaps a follikulitov). It should not be cause ointment immediately after baths to avoid increasing. You can not combine this treatment with ointment ultraviolet radiation. Not allowed into masi forever and eyes. With caution be applied ointment to easily razdrazhaemye of skin, especially among women (breasts, etc.).

     Treatment is usually continued 3 to 5 weeks.

     Treatment must be carried out under the supervision of a doctor. Systematic (1 week) morphological study of the blood. If you use drugs increasing erythema and itching of the skin, stop treatment (typically 2 - 3 days) to address these phenomena, and then assign lower concentration (1:100 000). If irritation resumed treatment ceased.

     After treating patients should avoid long exposure to intense sun.

     In gnezdnom serve ointment "Antipsoriatikum" rubbing concentration 1:100 000, moving to a concentration 1:40 000. Rubbing one day every day, long before the emergence of erythema, and then make a break before her disappearance, and again rubbing. Head wash every 7 days.

     In case of hypersensitivity to the drug may cause allergic skin, worsening psoriasis, skin irritation. After preparation on the ground causing pigmentation is slowly dying after preparation.

     The drug is not suitable for high sensitivity to it, diseases of liver, kidneys, blood-forming organs, dermatitis, eczema, in progressive stages, and with a propensity to piodermii and allergic reactions. Increased susceptibility to the drug can develop in the treatment process.

     With great care should be appointed ointment "Aptipsoriatikum when psoriaticheskoy eritrodermii. Ointment applied in concentrations of 1:100 000, not vtiraya it vigorously and placing wax paper. When even small signs of deterioration treatment ceased.

     Product type : the aluminium tubes of 25 and 95 g. and the glass on the banks of 40, 50 and 60 g.

     From preparations and work with it should proceed with caution.

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