ANDEKALIN (Andecalinum).

     Cleaned extracted from the pancreas of pigs not containing insulin.

     Liofilizirovannny powder or porous mass of white or yellow. Mg in the water.

     Lowers AD, increasing the peripheral blood vessels.

     Standardized products are biological method (for the reduction of animal AD).

     In clinical practice andekalin used for injections and andekalin tablets covered with skin.

     Andekalin for inektsny (A ndecalinum on injectionibus p r) issued in hermetically ukuporennyh bottles capacity of 5 ml (40-units of ED-derived product).

     Each bottle is attached solvent-1, 4 ml of 20% polyvinylpyrrolidone (relative molecular mass of 12600 + 2700). Diluted dissolve immediately before use, by the solvent in a bottle through a rubber tube piercing. Solution transparent, slightly yellow in the yellow color; PH 5, 5, 7, 0.

     Andekalin tablets covered with a white envelope (s Ta bulet A ndecalini on bduct s) containing 0,005 g andekalina, an ED 15.

     Applied andekalin with peripheral vascular disease and related food violations : in the form of spastic endarteriita, Reino disease, weak healing wounds and ulcers; Sclerodermia, migraines, retinopathy, etc.

     Assign andekalin intramuscularly or inside. Primary treatment in medium and heavy forms of the disease are usually using andekalin injection, and maintenance therapy with milder forms of disease-medication in the form of pills inside.

     Intramuscularly give light cases of ED 10, in a heavy 40 - ED. Beginning with the introduction of a day, and then (after 2 - 3 injections) daily. The course of treatment 2 to 4 weeks.

     With the disappearance of symptoms, imposed on 40 ED 1 every 2 days. Treatment should not stop immediately, and gradually reducing the dose. After a 2 - 3-month interruption of treatment can be repeated.

     Dose andekalina set individually depending on the nature and severity of the disease, as well as type of treatment (primary or supporting). Inside take over food. Treatment starts with the admission of 30 ED (2 tablets) three times a day. In the absence of express therapeutic effect and good endurance at 6-10-day daily dose can be increased gradually over 2 to 3 weeks before the ED 135-180 (9-12 tablets) a day in a bad Portability-reduced gradually to 40 60 ED (3 to 4 tablets) a day. Duration of treatment 1 month, during which take from 2250 to 3000 ED (150-200 tablets).

     After a two-month break -3 treatment can be repeated (There is evidence that andekalin be applied in small doses, because it contains kininrazrushayuschie enzymes, and in high doses can cause destruction bradikinina and its salts to relax.) .

     In intramuscular andekalina a possible allergic reaction, if you should have to cancel the appointment protivoallergicheskuyu and drug therapy.

     When taken tablets can be diarrhoeal, requiring the lifting of the preparation.

     Contraindications : neoplasia, and increased intracranial pressure.

     Method of issuance : andekalin injection (dried) in a package of five bottles of solvent applications; Pill-coated, in a package of 50 pieces.

     Storage : a dry product (dried) remain in a dry place at a temperature no higher than 18 C.

     In dissolved form can be stored in the vial longer than three to five days' S (in the refrigerator); Pill-dry at a temperature no higher +20' C.

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