AMILNITRIT (Amylii nitris).

     Izoamilovy nitrous acid ester.

     C inonimy : Amylium nitrosum, Amylis nitris, Isomilnitrit, Pentamylon, Vaporole.

     Transparent yellowish, legkopodvizhnaya very volatile liquid fruity smell. Easy to ignite. Very little is soluble in water; Mixed in all relationships with alcohol, ether, chloroform. The density of 0,869 - 0,879.

     Amilnitrit is the main representative of organic nitrogen. Back in the late 60 years of the last century was discovered properties of the compounds by inhaling fumes cause increased blood vessels and nausea breast stroke museum (strokes).

     In those years, it was recommended patients breast Toad wet piece of cloth a few drops (5 - 10) amilnitrita and inhale vapours. The drug began to work through 30-60. Simultaneously with the end zagrudinnyh Blush was more evolved person and headache (due to increased vascular brain).

     With the advent of nitroglycerin and its effectiveness in detecting strokes, amilnitrit in connection with pronounced side effects and short steps were appointed less.

     Currently amilnitrit as antianginalnoe means not being implemented. Only in exceptional cases, where there is no other antianginalnyh funds, it may be temporarily used for cupping the strokes.

     However amilnitrit, found use as an antidote to poisoning by cyanide, and its salts, because the ability amilnitrita (and other nitrogen) to form blood metgemoglobin linking ion S N, and to prevent this destruction of tissue respiratory enzymes.

     Applied amilnitrit through inhalation after causing it to bow shawl, a small piece of cotton or gauze. Assign an adult to 2 to 3 drops, children (over 5 years) - 1 - 2 drops.

     Higher doses for adults (for inhalation) : single 0.1 ml (6 drops); Daily 0.5 ml (30 drops).

     When cyanide poisoning his re-apply for the above doses (up to a total dose of 0.5 to 1 ml).

     Indications are the same as for nitroglycerin.

     Product : in conventional capsules and ampoules with Cotton marlevoy sheathing (for 0.5 ml). Autopsies vials accompanied by light explosion at the vapour pressure generated in vials in storage and heating. Couples amilnitrita form explosive mixtures with air.

     Storage : List B. In potted sealed in a cool place protected from the light.

Materials allowed to copy only with the active hyperlink to the handbook of medicines