AMPITSILLIN (Ampicillinum). 6-[D (-) - a-Aminofenilatsetamido] - penitsillanovaya acid.

     Synonyms : Pentreksil, Abetathen, Acidocycline, Acilin, Acrocilin, Agnopen, Albercilin, Amcil, Amecillin, Ampen, Ampexin, Ampifen, Ampilin, Ampiopenil, Amplenil, Amplital, Bactipen, Biampen, Binotal, Britapen, Broadocilin, Cimexillin, Diaciclin, Dicillin, Domicillin, Domipen, Eurocillin, Fortapen, Grampenil, Isticilline, Lificil1in, Maxibiotic, Maxipred, Morepen, Negopen, Opicilin, Oracilina, Penberin, Penbrock, Penibrin, Pentrex, Pentrexil, Pentrexyl, Policilin, Riomycin, Roscillin, Semicillin, Sintelin, Synpenin, Totacillin, Ultrabion, Vampen, Vexampil, Vidopen, Zymopen and others.

     Melkokristallichesky powder white, bitter-tasting; The acid resistant. Little is soluble in water, virtually nerastvorim of alcohol.

     Semi-ampicillin antibiotic obtained by synthesis 6-aminopenitsillanovoy acid balance aminofeniluksusnoy acid.

     Does not destroyed the acid stomach, well absorbed by ingestion. Active against gram microorganisms, which operates benzylpenicillin. In addition, it operates a number of micro gram [salmonella, shigella, proteus, Escherichia coli, Klebsiella pneumonia (wand Friedlander), wand Pfeyffera (wand influenza)] and, therefore, is seen as a broad-spectrum antibiotic and is applied in cases arising from the mixed infection.

     At penitsillinazoobrazuyuschie staphylococci resistant to benzylpenicillin, ampicillin is not acting as penitsillinazoy destroyed.

     Ampicillin applied for the treatment of pneumonia patients, bronhopnevmoniyami with abscesses light, angina, peritonitis, cholecystitis, sepsis, intestinal infections and postoperative infection in the soft tissue and other infections caused by susceptible to the microorganism.

     The drug has a high efficiency with a urinary tract infection caused by coliform bacilli, Protea, enterokokkami or mixed infection, as it provides an unaltered with the urine in high concentrations. In large quantities ampicillin is also in the bile. The drug is effective in the treatment of gonorrhea.

     Assign inside ampicillin (regardless of the meal). Razovyaya dose for adults 0.5 grams daily 2 - 3 g. Children appoint a rate of 100 mg / kg. The daily dose divided into 4-6 receptions.

     The length of treatment depends on the severity of disease and the effectiveness of therapy (5 - 10 days before the 2 - 3 weeks or more).

     When treating ampicillin could experience allergic reactions in the form of a skin rash, urticaria, swelling Kvinke etc., in rare cases, anaphylactic shock (mainly to the introduction of ampicillin sodium salt).

     If there allergic reactions to drugs and stop the introduction of a desensibiliziruyuschuyu therapy. When signs of anaphylactic shock must be taken urgently to remove the patient from the state.

     In long-term care ampicillin, a weakened patients may develop superinfektsii caused by microorganisms resistant to the drug (drozhzhepodobnye mushrooms, gram-negative microorganisms). These patients to appoint a Group B vitamins and vitamin C, if necessary, nystatin or levorin.

     The drug is not suitable for high sensitivity to penicillin. When liver failure by using liver function; In bronchial asthma, hay fever and other allergic diseases, as needed, while antisense designate funds.

     Ampicillin aggravating anti peroralnyh.

     Method of production : tablets and capsules to 0.25 grams in a package of 10 or 20 pieces.

     Available as ampicillin powder 5 g for suspension. Powder white with a yellowish sheen (sweet taste), with a specific smell (contains sugar, vanillin and other fillers). Is the interior in the same dose that ampicillin.

     Product : powder in banks orange glass on 60 g (5 g of the active substance). Is the rate of the active substance. Mix the powder with water or ?high water.

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