AMMIFURIN (Ammifurinum).
Contains a mixture of three furokumarinov : izopimpinellina, bergaptena (see) and ksantotoksina (see), isolated from plant seeds SDC large (A mmi majus L.), herewith. umbrella (Umbellifer s).
Light yellow or light yellow with a greenish white crystalline powder and odourless. Almost nerastvorim in the water, little is soluble in alcohol, easy-to chloroform.
Chemically similar to beroksanu. An integral part of both drugs is bergapten and izopimpinellin is 5, 8-dimethoxy-6, 7-furokumarinom, ie with relatively bergaptenom and ksantotoksinom contains additional group OCH said.
Step ammifurina, testimony to the application, possible complications and contraindications such as when applying beroksana.
The drug taking inside after eating, squeezed milk, dose 0.8 mg / kg, but not more than 0.08 grams of admission, one for 2 h before UV irradiation. External cause 0.3% solution in areas affected for 1 hour before irradiation.
Heading dose is 100-150 pills (2 - 3 g) or 1 - 2 bottle 0,3% solution (0,15 - 0,3 g). Repeated courses through a 1 -1, 5 months.
Patients with limited preparation of defeat sometimes appoint only External (in combination with ultraviolet irradiation).
There is a positive experience ammifurina method PUVA- therapy.
Method of production : tablets of 0.02 grams in a package of 100 pieces; 0.3% solution in orange glass bottles of 50 ml.
Storage : List B. In the dark, cool place.
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Materials allowed to copy only with the active hyperlink to the handbook of medicines
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