AMIKATSINA SULFAT (Amikacini sulfas)

     Substances [4-Amino -2 - (S) - gidroksibutiril] -0-6 - amino-6- dezoksi a -D- glyukopiranozil - (1-> 4)] - O-[3-amino-3- dezoksi a -D- glyukopiranozil - (1-> 6)] 2-dezoksi-D- streptamina disulfat.

     Synonyms : Amikacin sulfate, Amikin, Amitrex, Buklin, Briclin, Fabianol, Kanimax, Likacin, Lukadin, Sifamic.

     Amorphous powder white or white with a yellowish sheen color. The easily soluble in water. Gigroskopichen.

     Received by a semi kanamycin A.

     He is one of the most active Antibiotic aminoglikozidov. It has a wide range of antimicrobial activity. Effective against gram especially gram of bacteria.

     Applied intramuscularly and intravenously. Indications for use are the same as for other antibiotikav- aminoglikozidov imposed parenteral (see Tobramitsin, Kanamitsin, Gentamitsin, Sizomitsin).

     Solutions amikacin sulfate prepared immediately before use. For intramuscular introductions dissolve the contents of a bottle (0.25 - 0.5 g) in 2 - 3 ml of sterile water for injection. For intravenous (drip impose a speed of 60 drops per minute) offers the same solution, which is to throw in 200 ml isotonic sodium chloride solution, or 5% glucose solution. Amikacin concentration of the solution in giving veins should not exceed 5 mg in 1 ml.

     Either way, entering (adults) at 0.5 g product 2 - 3 times daily for 7 to 10 days.

     In a normal urinary tract infection (with the exception of infections caused by Escherichia Coli) intramuscularly to impose 0.25 g 2 times a day for 5 to 7 days.

     The maximum daily dose of 1, 5 g.

     If the renal excretory function of dose reduce or increase the interval between injections.

     In the absence of therapeutic effect within 5 days of treatment over other drugs.

     Possible complications and contraindications such as the application of other Antibiotic aminoglikozidov.

     Product : to 0.1; 0.25, or 0.5 grams hermetically ukuporennyh glass bottles (in the form of porous white or white with a yellowish sheen color).

     Storage : dry, the dark place at room temperature.

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