AMIDOPIRIN (Amidopyrinum). Fenil-1 - 2, 3 - dimethyl Dimethylamino pirazolon-5.

     Synonyms : Piramidon, Alamidon, Amidazophen, Amidofebrin, Amidophen, Amidopyrazoline, Amidozon, Aminophenazonum, Aminophenazone, Aminopyrin, Anafebrine, Dimapyrin, Dipyrin, Novamidon, Pyramidonum, Pyrazon and others.

     White crystals or a white crystalline powder odourless, slabogorkogo taste. Slowly soluble in water (1:20), easily soluble in alcohol (1:2). The solutions (pH 7, 0-7, 8) in sterile + 100 C for 30 min.

     Has cough, and has an anti-inflammatory effect. On pharmacologically Amidopyrine close to antipirinu, but increasingly it.

     Applied with headache, neuralgia, arthritis, scoliosis, trochaic, sometimes with acute rheumatic fever.

     In connection with a better portability as analgeziruyuschih funds are used analgin and Paracetamol (see).

     Several earlier finished dosage forms containing Amidopyrine, excluded from the range of medicines. But some combination therapies (pill-see below) in the nomenclature is preserved.

     Amidopyrine applied to the interior of 0.25 - 0.3 g 3 - 4 times a day. In acute stroke rheumatism designate up to 2 to 3 grams a day.

     Children, depending on age appoint 0,025 - 0,15 g per reception. When treating rheumatoid arthritis may be increased to a daily dose of 0,15 - 0,2 g for 1 year of life (4 admission).

     Higher doses for adults inside : single 0.5 g daily 1, 5 g.

     In long-term care amidopirinom to periodically study blood, as in some cases there may be a blood oppression (granulotsitopeniya and agranulotsitoz). Sometimes you see skin rashes. An individual cases anafilakticheskih reactions.

     Amidopyrine out from the body primarily from urine. Products its dissolution (rubazonovaya acid, etc.) can give urine dark yellow or red colour.

     Method of issuance : powder; Tablets of 0.25 g and tablets containing 0.25 g amidopirina kofein- and sodium benzoate 0.1 g.

     Storage : List B. In the dark spot.

     Pills <<Novomigrofen>> (Tabulettae <<N of about migrophenum> v>). Forty amidopirina 0.2 g fenatsetina 0.1 g, 0,015 g of caffeine, citric acid 0,015 g.

     Pills <<Piramein>> (Tabulettae <<Pyrameinum>>). Forty amidopirina 0.3 g caffeine 0.03 g.

     Pills <<Pirafen>> (Tabulettae <<Pyraphenum>>). Forty amidopirina and fenatsetina to 0.25 g.

     Pills <<Pirkofen>> (Tabulettae <<Pyrcophenum>>). Forty amidopirina and fenatsetina to 0.25 g, 0.05 g. caffeine

     All these pills used in headache, neuralgias, frenzied state; Appoint one pill 2 to 3 times a day.

     Pills <<Amazol>> (Tabulettae <<Amaz on lum>>). Forty amidopirina 0.3 g dibazola 0.02 g.

     Applied as infections and salts in case of hypertension, migraines. Assign to one pill 2 to 3 times a day.

     All the pills are to list B.

     Pills and amidopirina butadiona to 0.25 g (see Phenylbutazone, Reopirin).

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