AMBROKSOL (Ambroxolum) *. trans-4- [(2-Amino-3, 5-dibrombenzil) amino] cyclohexanol hydrochloride.
Synonyms : Lazolvan, Lasolvan, Ambrolitic, Bronchopront, Fluixol,
Lindoxyl, Mucofar, Mucosan, Mucosolvon, Mucovent, Secretil, Viscomcil and others.
White powder Cree c tallichesky odourless, slightly bitter taste.
On chemical structure similar to bromgeksinu. Is the absence of last methyl group with side chain nitrogen atom and a guide roksila in geksilnogo parameters of the kernel.
On pharmacological properties and mechanism of action ambroksil a major port is different from bromgeksina. Both are mucolithic media involved, promote education surfaktanta, normalizuyuschimi measuring elaborate bronchopulmonary secretion, improving the flow rates may moles, reducing its viscosity and adhesive properties to facilitate its removal from the bronchi.
Amboroxol (lasolvan) attracted much attention in the general media interest in promoting education surfaktanta.
Indications for use mainly the same as for bromgeksina.
Amboroxol (lasolvan) was not substantially different from bromgeksina to influence the products and surfaktanta mukotsiliarny transportation. There is a decree that amboroxol can also be used for stimulation of Education surfaktanta for premature babies and babies with the syndrome patient advocacy failure.
Adults amboroxol (lasolvan) designate the interior of one pill (30 mg) three times a day; While long-term care for one pill two times a day. In feature after eating a small amount of water.
Детям рекомендуется давать в виде сиропа (15 мг амброксола в 5 мл) в следующих дозах: до 2 лет - по 2, 5 мл 2 раза в день, от 2 до 5 лет - по 2, 5 мл 3 раза в день, старше 5 year-to 5 ml of 2 - 3 times a day. In the first 2 or 3 days of treatment dose can be doubled. Adults designate syrup in the first 2 - 3 days to 10 mL three times a day, followed by 5 mL three times a day.
Амброксол (ласольван) можно также применять в виде раствора для ингаляций (15 мг в 2 мл): у взрослых и детей старше 5 лет - по 1 - 2 ингаляции в день по 2 - 3 мл; у детей до 5 лет - по 1 - 2 inhalations per day to 2 ml.
The drug can be administered intravenously or intramuscularly. Adults enter for 2 to 3 capsules (15 mg vials in) 2 to 3 times a day; Children up to 2 1 / 2 capsules two times a day; From 2 to 5 years - 1 / 2 capsules three times a day, over five years - one ampoule 2 - 3 times a day. When respiratory syndrome is not sufficient to impose a rate of 10 mg / kg / day (3 - 4 admission).
The drug is usually well. In some cases, when administered possible nausea and vomiting.
There should be appointed amboroxol in the first three months of pregnancy.
Method of issuance : to 30 mg tablets in a package of 50 pieces; Capsules containing 15 mg of the drug; Syrup containing 15 mg drug in 5 ml, in a package of 100 ml; For inhalation solution containing 15 mg drug in 2 ml of packing 100 ml.
Materials allowed to copy only with the active hyperlink to the handbook of medicines