ALPROSTADIL (Alprostadil).

     The preparation of a group of prostaglandines (prostaglandin E).

     Synonyms : Vazaprostan, Prostavazin, Minprog, Prostandin, Prostavasin, Prostin VR, Vasaprostan.

     It is reducing uterine muscles, intestines and other organs gladkomyshechnyh, but has expressed a peripheral salts, increases blood flow to peripheral vascular, improves inhibits platelet aggregation and has dezagregatsionnoe effect.

     Used mostly for chronic diseases obliteriruyuschih lower extremity arteries (atherosclerosis obliteriruyuschy etc.).

     The drug is more effective in phase II and III ischemic lower limbs.

     Alprostadil applied intravenously and vnutriarterialno.

     For intravenous use of the contents of two vials (40 µ g of preparation) to throw in 250 ml isotonic sodium chloride solution. Enter drip (within 2 hours) one time, and in severe cases, two times a day. If there is a need to increase the dose of 60 µ g (3 capsules) and enter within 3 h.

     In vnutriarterialnom introduction to throw 20 µ g (1 vials) in 50 ml isotonic sodium chloride solution. First introduced 10 µ g (1 / 2 capsules, 25 ml) for 60 min, 120; With good endurance in the future can be administered 40 µ g (during the same time). Injections produce 1 to 2 times daily. A long cefuroxim through the catheter.

     The course of treatment is continuing 15-25 days.

     In applying alprostadila possible decline in blood pressure, loss of appetite, diarrhoea, blunt pain in the limbs, exposed to treatment, a feeling of burning, Blush in place a catheter.

     The drug is contraindicated in pregnancy and breastfeeding.

     Please note that alprostadil increases hypotensive effect and antiagregatsionnyh funds.

     Product : in ampoules containing 0.02 mg (20 µ g) alprostadila, 10 vials of the pack.

     Storage : List B. In the dark place at room temperature.

     Solutions prepared immediately before use.

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