ALLOKSIM (Alloximum).

     N-Allil-2- piridinaldoksima bromide. The structure is close to dipiroksimu.

     White or white with a yellowish sheen crystalline powder. Available in the form of dried white or yellow-white powder and porous, water soluble.

     Is reaktivatorom cholinesterase. Implemented in acute poisoning by organic phosphorus compounds in combination with atropine or other holinoliticheskimi drugs).

     Enter or intramuscularly once again depending on the severity of poisoning.

     Before applying the contents of capsules (0,075 g product) dissolving in 1 mL of sterile water for injection.

     In early signs of poisoning (initiation, cramps, sweating, slyunootdelenie, primary phenomenon bronhorei) entering into the skin 2 to 3 ml of 0.1% solution of atropine sulfate and within myshechno alloksim dose of 0,075 grams of 60-70 kg of body weight patient. If poisoning symptoms do not disappear in 2 to 3 hour re-introduce drugs in the same doses.

     In more severe form of poisoning injected 3 ml of 0.1% rasvora atropine sulfate, 5 to 6 minutes intravenous atropine in the same dose again to a complete halt bronhiolospazma phenomena and the development of atropinizatsii. At the same time introducing alloksim dose of 0,075 g intramuscularly to the interval between injections of 1 to 3 hours

     Cure rates are visible improvement Bioelectrical activity of the brain (the normal <-rhythm), ending miofibrillyatsy and enduring increasing blood cholinesterase activity.

     Under the dose alloksima 0,075 grams daily doses of 0.2, 0.8 g. total dose is 0.4 to 1, 6 g.

     Alloksim in combination with atropine shown to apply not only with the symptoms of poisoning, but if not, when it is known that a lethal effect on the organism (oseltamivir).

     Product : dried porous mass or powder in capsules of 0,075 grams (75 g) (A lloximum li-op hilisatum 0,075 p r on injectionibus) in a package of 10 vials of applications solvent (1 mg of sterile water for injection).

     Storage. : List B. In the dark spot in the temperature does not exceed + 10 C.

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