AYMALIN (Ajmalinum).

     Alkaloid contained in certain rauvolfii (Rauwolfia a serpentin We nth. Etc.) (See Reserpine.) .

     On chemical structure of the group of indole derivatives.

     C inonimy : Ajmaline, Arythmal, Cardiorythmine, Gilurytmal, Ritmos, Tachmalin and others.

     White or white to slightly yellowish sheen crystalline powder. Very little is soluble in water, it is difficult to alcohol. Aymalina acetate hydrochloride and easily soluble in water.

     Aymalin (unlike rezerpina also contained rauvolfii) is not neurotic activity, moderate AD lowers slightly increases coronary blood flow, has a negative effect inotropny and moderate adrenoliticheskoe effect.

     Feature aymalina properties are complications. It reduces anxiety attack, refrakterny lengthens the time constraint and atrioventrikulyarnuyu vnutrizheludochkovuyu conductivity, injures several automatic sinusnogo hub suppresses impulsoobrazovanie Cumulative pockets of automaticity. Referring to the complications I medication group.

     Aymalin able nausea and vomiting mertsatelnoy keep paroksiz singled tachycardia.

     Also effective rhythm of the violations related to drug intoxication lapidary.

     Assign intravenously, intramuscularly, and the interior; More efficient at parenteral introduction.

     For acute edema mertsatelnoy adults and paroxysmal tachycardia injected 0.05 g (2 2 ml, 5% solution) in 10 ml isotonic sodium chloride solution, or 5% glucose solution. Enter slowly within 7 to 10 minutes. If necessary, during the day you can still re-enter the city may impose 0.05 medication drip : 2 - 4 2 ml, 5% solution in the 100-to 200 ml isotonic sodium chloride solution. Intramuscularly imposed on the 0.05 g (2 2 ml, 5% solution) every 8 h to 0.15 g / day (ie, up to 3 times). If necessary, introduce a product few days.

     Once the therapeutic effect of injecting drugs moving to a reception inside the 1 - 2 tablets (0,05 - 0,1 g) 3 - 4 times a day (within 1 to 3 weeks).

     Aymalin usually well. For some patients were hypotension, weakness, nausea, vomiting; When intravenously, is the feeling of warmth.

     Contraindications (especially intravenous) : heavy defeat following a heart, has expressed sclerosis and inflammatory changes in heart, circulatory insufficiency III extent sharp hypotension.

     Caution is necessary when introducing aymalina patients with recent myocardial infarction : possible downgrading of AD and violation conductivity.

     Method of production : tablets of 0.05 g; 2, 5% solution in ampoules of 2 ml (25 mg in 1 mL).

     Storage : List B. In the dark spot.

     R p. : Ta b. A jmalini 0.05 N.20

     D.S. At one tablet three times a day

     R p. : S for l. Ajmalini 2, 5% 2 ml

     D.t.d. N. in ampull 10.

     S. 2 ml in 10 ml of intravenous 5% glucose solution.

     Enter slowly.

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