ETIMIZOL (Aethimizolum).

     BIS (metilamid) -1 - etilimidazol-4, 5-TEDA acid.

     The white crystalline powder. Few soluble in water, soluble in alcohol. Aqueous solutions pH (6, 5-7, 2) to sterilize + 100 C for 30 min.

     Etimizol has a catalytic effect on the respiratory center and belongs to the group of respiratory analeptics, however, it activates adrenokortikotropnuyu pituitary function, which leads to increased levels of glucocorticosteroids in the blood. There is also evidence that short etimizol improves memory and increases mental performance.

     As a catalyst for breathing etimizol apply to drug poisoning and analgetikami, during and after the general anastezii with lung atelectasis and other conditions involving gipoventilyatsiey light. There is evidence of the use etimizola with asphyxia and postasfiksicheskih condition of the babies.

     Because of the stimulation adrenokortikotropnoy pituitary function etimizol used as anti-vehicle and antiallergicheskoe in medicine, polyarthritis, as well as some forms of bronchial asthma. Bronholiticheskoe of drug partly due to his moderate spazmoliticheskimi properties.

     In the mechanism of action etimizola a role can play its inhibition effect on fosfodiesterazu leading to the accumulation in the tissues of cyclical AMF (see Kofein).

     To stimulate breathing etimizol impose adult intramuscularly or intravenously (slowly) in a 1 or 1%, 5% solution rate of 0.6 to 1 mg per 1 kg of body weight patients (0,03 - 0,06 g per patient) 1 two times a day. As bronholiticheskoe funds with a relatively easy course and a small length of the disease (in patients suffering bronchial asthma and bronchitis) designate the interior of 0.1 g 3 to 4 times a day or intramuscularly 1 to 2 ml, 5% solution of 2 times a day.

     As anti antiallergicheskoe funds and designate the interior (of tablets) to 0.1 g 3 - 4 times a day (after eating). The course of treatment 20 to 30 days.

     Using the drug inside can be nausea and other diarrhoeic phenomenon. Sometimes there is anxiety, dizziness, sleep violations. In these cases, reduce single dose of up to 1 / 2 tablets, appointing 5 to 6 times a day, excluding evening; If development diarrhoeic events to take drugs through half an hour after eating.

     The product should not appoint a patient with motor and mental stimulation.

     Method of issuance: powder; Tablets of 0.1 g; 1 or 1%, 5% solution in the ampoule on 3 and 5 ml.

     Storage: List B. In sheltered from the world scene.

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