Pipemidievaya acid (acidum pipemidiecum)


PIPEMIDIEVAYA ACID (Acidum pipemidiecum). Piperazin-5- 2-oxo-8 - ethyl-5, 8-digidro- pirido (2 3-d) pirimidin-6- - carboxylic acid.
     Synonyms : Palin, Acipem, Balurol, Cistomid, Filtrax, Naril, Palin, Pimidel, Pipedae, Pipefort, Pipemidic acid, Pipram, Pipurin, Septidron, Solupemid, Uripan, Urisan, Urixin, Urodipin, Uromidin, Uropimid, Urosetic, Uroval et al .
     On chemical structure can be modified as nalidixic acid molecules.
     Yellowish white powder with a bitter taste, Darkling under the influence of light.
     The drug has antimicrobial activity. Active against Pseudomonas, associated with the presence of molecules piperazinovogo nucleus.
     In clinical practice acid pipemidievaya particularly effective in the acute and chronic urinary tract infection routes.
     Adults are inside of 0.4 g (0.4 g 1 tablet or two capsules of 0.2 g), 2 times a day (morning and evening). The course of treatment is 10 days or more, depending on the course of the disease.
     Children from 1 year to 15 years, appoint a rate of 15 mg / kg, divided by 2 admission.
     Women are encouraged to re-infection with the reception inside, to nominate one vaginalis candle each day during the July 10 days.
     In applying the drug may allergic skin reactions, nausea, stomach pain, a phenomenon photosensitization.
     Contraindicated in pregnancy. Caution should be observed in renal failure. Children taking medicine, which should be under careful medical supervision.
     During treatment to support enhanced Diurez.
     Method of issuance : capsules in 0.1 and 0.2 g; Tablets of 0.4 g; Vaginal candles 0.2 g; Suspension (for children) in bottles of 100 ml containing 100 mg (0.1 g) 5 ml.
     Storage : List B. In the dark spot.

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