ASKORBINOVAYA ACID (Acidum ascorbinicum).

     VITAMIN C (Vitaminum C). g-Lakton 2, 3-degidro-L- gulonovoy acid.

     Synonyms : Acidum ascorbicum, Ascorbin, Ascorbit, Ascorvit, Cantan, Cantaxin, Cebione, Cecon, Celin, Ceneton, Cevalin, Cevex, Laroscorbine, Redoxon, Scorbumine, Vicin, Vitascorbol and others.

     The white crystalline powder acidic taste. The easily soluble in water (1:3, 5), is soluble in alcohol. Solutions for injection prepared with the addition of sodium gidrokarbonata and stabilizers; When sterile + 100 C for 15 min; Solutions pH 6, 0, 7, 0.

     Ascorbic acid (vitamin C) can be found in large quantities in products of plant origin (fruit pest, cabbage, lemons, oranges, fruit, fruit, berries, pine, etc.). Small quantities of vitamin C are in animal products (liver, brain, muscles). For medical purposes ascorbic acid synthetic get through.

     Ascorbic acid plays an important role in the life of the organism. Thanks to the availability of a molecule dienolnoy group (=-SON-SON), it has expressed strong recovery properties. Participates in the management of okislitelnovosstanovitelnyh Carbohydrate exchange, blood coagulability tissue regeneration, education steroid hormones. One of the major physiological functions of ascorbic acid is its participation in the synthesis of collagen and prokollagena and normalize capillary permeability.

     The human body is unable to synthesize vitamin C; Need it be granted vitamin enlisted with food. The lack or absence of it leading to hypo - or beriberi (scurvy).

     Daily demand for ascorbic acid is an adult 70-100 mg; For children between the ages of 6 months to 1 year, 20 mg; 1 to 1, 5 years, 35 mg; 1, 5 and 40 mg 2 years ; from 3 to 4 years, 45 mg; from 5 to 10 years, 50 mg; from 11 to 13 years, 60 mg; boys 14-17-80 mg; girls 14 to 17 years - 70 mg.

     Crystal containing ascorbic acid and its products used in preventive and curative purposes in all cases when the body needs further introduction of the vitamin : to prevent and cure scurvy and haemorrhagic diathesis, nose, lung, liver, uterine and other krovotecheniyah; Including caused by radiation sickness, as well as anti-overdose in infectious diseases and poisoning, liver disease, nephropathy pregnant, Edison disease, weak healing wounds and broken bones, malnutrition and other pathological processes. Preparation is also nominated in labour intensive physical, mental stress during pregnancy and lactation.

     While the positive impact of ascorbic acid on lipid exchange with atherosclerosis.

     Assign ascorbic acid interference (after eating), intramuscularly or intravenously.

     Preventively designate an adult to 0.05-0.1 g / day; During pregnancy, the postpartum period and in the case of low vitamin C content in the milk of lactating women appointed to 0.3 grams per day for 10 to 15 days, then oseltamivir to 0.1 grams per day throughout the period of lactation.

     Children designate oseltamivir to 0,025 g 2 - 3 times a day.

     Therapeutic dose for adults is when administered 0.05-0.1 g 3 - 5 times a day; Parenteral impose a solution sodium salt (sodium askorbinat) 1 - 3 ml of 5% solution.

     Children designate the interior of 0.05-0.1 g 2 - 3 times a day; Parenteral 1 to 2 ml of 5% solution.

     Timing of treatment depends on the nature and techennya disease.

     Ascorbic acid is usually well. Nor should appoint high doses to patients with high blood coagulation, throm and prone to brain, as well as diabetes.

     With long-term use of large doses of ascorbic acid might oppression functions insulyarnogo apparatus pancreas, it is in the process of treatment should regularly monitor the functional ability of the latter. Because of the incentive effects of ascorbic acid education corticosteroid hormones in the treatment of large doses needed to monitor kidney function and blood pressure.

     Method of issuance : powder; Tablets of 0.05 and 0.1 g (for adults); Pills to 0,025 g (for children); Pills to 0,025 g of glucose (proactive), 5% and 10% solutions in ampoules of 1 and 2 ml (for medicinal purposes).

     Solution ascorbic acid injection (5%) of 2, 385 g sodium gidrokarbonata for every 5 g of ascorbic acid; Thus, when entering sodium injection askorbinat (5% solution of pH 6, 0, 7, 0).

     Ascorbic acid is produced as tablets with routine (see Pills "Askorutin"). Moreover, it was part of the combined (multivitamin) tablets (see Asnitin, Undevit, Aerovit, Geksavit etc.).

     There are pills containing ascorbic (0.1 g) and folic (0.0008 grams) acid (see folic acid).

     Storage : ascorbic acid powder in the well-ukuporennoy packaging keeps out of light in a cool, dry place; Tablets and capsules, in a cool place protected from the light.

     Rp. : Ta b. As. a scorbinici 0.05 N. 50

     D.S. For two tablets three times a day (after eating)

     Rp. : Sol. As. scorbinici 5% and 1 ml

     D.t.d. N. in ampull 20.

     S. At 1 ml of muscle 2 times a day

     The so-called "Magnesium askorbinat has a magnesium salt solution ascorbic acid in combination with glucose solution (see Glucose).

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