Universal reference book for medicines
Product name: EXPORTAL (EXPORTALE)

Active substance: lactitol

Type: Laxative preparation with osmotic properties

Manufacturer: FPK FarmVILAR (Russia) manufactured by FPK FarmVILAR (Russia)
Composition, form of production and packaging
Powder for solution for ingestion
white, crystalline.

1 pack.

lactitol monohydrate 5 g

5 g - single dose bags (2) - strips (3) - cardboard packs.

5 g - single-dose bags (2) - strips (5) - cardboard packs.

5 g - single-dose bags (2) - strips (6) - cardboard packs.

5 g - single-dose bags (2) - strips (10) - cardboard packs.

Powder for solution for ingestion white, crystalline.

1 pack.

lactitol monohydrate 10 g

10 g - single-dose bags (2) - strips (3) - cardboard packs.

10 g - single-dose bags (2) - strips (5) - cardboard packs.

10 g - single dose bags (2) - strips (6) - cardboard packs.

10 g - single-dose bags (2) - strips (10) - cardboard packs.

Powder for solution for ingestion white, crystalline.

1 container

lactitol monohydrate 200 g

200 g - plastic containers (1).

Powder for solution for ingestion white, crystalline.

1 container

lactitol monohydrate 500 g

500 g - plastic containers (1).

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2013.

PHARMACHOLOGIC EFFECT

Laxative drug.

In the large intestine, lactitol is split under the action of the intestinal flora into low-molecular organic acids, which leads to an increase in osmotic pressure in the large intestine, an increase in the volume of fecal masses, their softening, facilitating bowel movements and normalizing bowel function.
The laxative effect usually occurs within 24 hours after application of the drug (delay is due to the passage of the drug through the gastrointestinal tract). At the beginning of the course of treatment, the laxative effect of the drug may be delayed, the effect may occur on the second or third day of its use.
In patients with hepatic encephalopathy or hepatic coma (or precoma), the effect is achieved through the migration of ammonia from the blood to the large intestine (due to a decrease in PH, an increase in osmotic pressure in the lumen of the intestine), removal of detached ammonium ions and other nitrogen-containing toxic substances from the colon.

Lactitol suppresses proteolytic bacteria and increases the number of acidophilic bacteria.

PHARMACOKINETICS

Lactitol has its effect only in the large intestine, where it completely falls after ingestion.
It is absorbed in minimal amounts in unchanged form (no more than 0.5-2% of the accepted dose).
INDICATIONS

- constipation;

- the need to regulate the chair for medical purposes (cleaning the intestine in preparation for endoscopic and radiographic research, surgical procedures on the rectum, anal sphincter and the area adjacent to it);

- intestinal dysbiosis;

- hepatic encephalopathy, hepatic coma and precoma, hyperammonemia.

DOSING MODE

The drug is prescribed inside while eating, mixing with various drinks (water, tea, coffee, juices) or liquid food.

With constipation and dysbiosis, the drug should be taken once, the entire daily dose at once, for 1 reception.

Children aged 1-6 years are prescribed 2.5-5 g (1 / 2-1 teaspoon of powder) / day;
children aged 6-12 years - 5-10 g (1-2 teaspoons of powder) / day; children aged 12-16 years - 10-20 g (2-4 teaspoons of powder) / day; adults - 20 g (4 teaspoons of powder) / day.
The drug should cause a stool 1 time / day;
after the onset of a stable laxative effect for several days of the drug, its dose can be reduced. In some cases, half of the recommended daily dose is sufficient to obtain the desired effect.
The minimum course of therapy, after which you should seek medical advice - 5 months.
The use of the drug in children is recommended to be carried out under the supervision of a doctor.
When adjusting the chair for medical purposes , 20 g of the drug diluted in 1 liter of water are taken 3 times (at 12, 15 and 18 h) on the eve of the medical procedures.

In hepatic encephalopathy, hepatic precoma and coma, hyperammonia, the dose of the drug should be selected individually for each patient, depending on the severity of the disease and individual response to the drug.
The initial daily dose is usually 500-700 mg / kg body weight. This dose is divided into 3 single doses. Take with food. A dose that causes two "soft" stools per day should be selected.
SIDE EFFECT

At the beginning of treatment, there may be a feeling of discomfort in the abdomen, flatulence.
These phenomena, as a rule, disappear with the continued use of the drug, as it adapts to it. In the case of using the drug in elevated doses for a long time in the treatment of hepatic encephalopathy, the patient, due to diarrhea, may develop electrolyte imbalance.
CONTRAINDICATIONS

- galactosemia;

- intestinal obstruction;

- Suspicion of organic lesions of the gastrointestinal tract;

- abdominal pain and rectal bleeding of unknown origin;

- Individual lactitol intolerance.

APPLICATION FOR CHILDREN

Children aged 1-6 years are prescribed 2.5-5 g (1 / 2-1 teaspoon of powder) / day;
children aged 6-12 years - 5-10 g (1-2 teaspoons of powder) / day; children aged 12-16 years - 10-20 g (2-4 teaspoons of powder) / day; adults - 20 g (4 teaspoons of powder) / day.
SPECIAL INSTRUCTIONS

Lactitol has a low calorie content (2 kcal / g), does not affect the level of glucose in the blood and can be used in patients with diabetes mellitus.

Throughout the course of the drug is desirable increased fluid intake.

Impact on the ability to drive vehicles and manage mechanisms

The use of Export does not affect the psychomotor functions associated with driving a car or controlling cars and machinery.

OVERDOSE

Symptoms: diarrhea, in rare cases, vomiting is possible.

Treatment: symptoms of an overdose are usually eliminated by lowering the dose of the drug.

DRUG INTERACTION

When concurrently taking Export with enteric-soluble drugs with pH-dependent release, it should be taken into account that lactitol lowers the pH of the intestine.

It is not recommended to use Exportal ® within 2 hours after taking other medicines.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored in a dry place, protected from light and inaccessible to children.
Shelf life - 5 years.
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