Universal reference book for medicines
Name of the preparation: ECOFUCIN ® (ECOFUCIN)

Active substance: natamycin

Type: Antifungal agent for topical application in gynecology

Manufacturer: АВВА РУС (Russia) manufactured by FARMEA (France)
Composition, form of production and packaging
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Suppositories vaginal from light yellow to light brown in color, torpedo-shaped; on the longitudinal section there should be no foreign inclusions; the presence of an air jet or a funnel-shaped depression is permitted.
1 supp.

natamycin 100 mg

Excipients: lactulose - 300 mg, macrogol glyceryl hydroxy stearate - 200 mg, silicon dioxide colloid - 20 mg, fat solid (Suppocir AM) - up to 2300 mg.

3 pcs.
- packings of cellular contour (1) - packs cardboard.
3 pcs.
- packings cellular planimetric (2) - packs cardboard.
6 pcs.
- packings of cellular contour (1) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2016.

PHARMACHOLOGIC EFFECT

Natamycin is an antifungal polyene antibiotic from the macrolide group, which has a wide spectrum of action.
It has a fungicidal effect. It binds to sterols of cell membranes, violating their integrity and function, which leads to the death of microorganisms.
It is active against most pathogenic yeast-like fungi (especially Candida albicans), yeast (Torulopsis and Rhodotorula), as well as other pathogenic fungi (Aspergillus, Penicillium).
Less active against dermatophytes (Trichophyton, Microsporum, Epidermophyton). Does not affect in vitro gram-positive and gram-negative bacteria.
Resistance to natamycin in clinical practice is not found.

PHARMACOKINETICS

Ecofucin ® does not have a systemic effect.
practically not absorbed through intact skin and intact mucous membranes.
INDICATIONS

- Vaginitis, vulvitis, vulvovaginitis caused by Candida mushrooms.

DOSING MODE

Suppositories, after having been released from the contour pack, are injected into the vagina, lying in the supine position, as deep as possible, 1 time / day for the night.

With candidiasis vaginitis, vulvitis, vulvovaginitis, intravaginal administration is used for 1 supp.
for 3-6 days.
With persistent flow of vaginitis caused by Candida albicans , additionally prescribed natamycin in the form of tablets for oral administration: 1 tab.
4 times / day for 10-20 days for sanation of the focus of candidiasis infection in the intestine.
The duration of the course of treatment is set individually.
After the disappearance of the symptoms of the disease is recommended to continue treatment a few more days.
During menstruation, the use of suppositories is interrupted.

SIDE EFFECT

With topical application, slight irritation and a burning sensation at the injection site are possible.

CONTRAINDICATIONS

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

It is possible to use Ecofucin ® in pregnant women and during lactation.

SPECIAL INSTRUCTIONS

With vaginal application under the influence of body temperature, suppositories turn into a foamy mass, which contributes to the uniform distribution of natamycin over the mucous membrane of the vagina.

During the period of treatment, there is no need to exclude sexual contact, but it is recommended to conduct a survey of sexual partners and, in case of candidal lesions, to treat with natamycin.
In the period of treatment, barrier methods of contraception should be used.
Impact on the ability to drive vehicles and manage mechanisms

The use of Ecofucin ® does not affect the ability to drive vehicles and mechanisms.

OVERDOSE

At present, no cases of an overdose of Ecofucin ® have been reported.

DRUG INTERACTION

Drug interaction of the drug Ecofucin ® with other drugs is not described.

TERMS OF RELEASE FROM PHARMACY

The drug is dispensed without a prescription.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored in a place protected from moisture and light, inaccessible to children at a temperature of no higher than 25 ° C.
Shelf life - 2 years. Do not use after the expiration date printed on the package.
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