? Cream for external use 1% of white to yellowish white, homogeneous, homogeneous, virtually odorless.
1 g
econazole nitrate 10 mg
Auxiliary substances: sodium hydroxide 0.9 mg, sodium dihydrogen phosphate dihydrate 3.65 mg, phosphoric acid 0.02 mg, chlorocresol 1 mg, cetomacrogol 1000-50 mg, cetostearyl alcohol (cetyl alcohol 60%, stearyl alcohol 40%) 70 mg, paraffin white soft - 150 mg, paraffin liquid - 60 mg, purified water - sk. demand. up to 1 g.
10 g - aluminum tubes (1) - packs of cardboard.
20 g - aluminum tubes (1) - packs of cardboard.
10 g - plastic laminated tubes (1) - cardboard packs.
20 g - plastic laminated tubes (1) - cardboard packs.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2013.
PHARMACHOLOGIC EFFECT
Econazole is an imidazole derivative, a broad-spectrum antifungal agent for topical application. It has fungicidal and bactericidal action. It inhibits the synthesis of ergosterol, which regulates the permeability of the cell wall of microorganisms. Active against dermatophytes, yeast and mold fungi:
Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, Candida albicans, Torulopsis, Rhodotorula, Malassezia furfur (Pityrosporum orbiculare), which causes pungent lichen, Corynebacterium, Epidermophyton floccosum, Aspergillus, Cladosporium, Scopulariopsis brevicautus and some Gram-positive bacteria (Streptococcus, Staphylococci and Nocardia minutissima). Effective against fungi, resistant to treatment with other drugs. With topical application causes death of fungi within 3 days, promotes rapid regression of burning and itching of the skin.
PHARMACOKINETICS
With external application, the drug penetrates all layers of the skin and the nail plate. Therapeutic concentrations are created in the horny and other layers of the epidermis, as well as in the dermis. When applied to the skin, systemic absorption is minimal and practically insignificant. Less than 1% of the applied dose is excreted with colic masses - the intestine, and the kidneys.
INDICATIONS
- dermatomycosis of the skin of the scalp caused by dermatophytes, yeasts, mold fungi, incl. complicated by superinfection with gram-positive bacteria;
- Erythrazma;
- colored lichen;
- skin infections caused by gram-positive microorganisms.
DOSING MODE
Outwardly.
Adults and children over 18 years : on the affected area of ​​the skin, apply the cream in a thin even layer and rub until absorbed 2 times a day (morning and evening).
Duration of application - 2 weeks, in the treatment of highly keratinized skin (stop) - up to 1.5 months.
SIDE EFFECT
Individual intolerance to econazole and other components that make up the drug.
Local reactions in the form of burning, itching, irritation and flushing of the skin, hives, dryness, hypopigmentation, skin atrophy are possible.
CONTRAINDICATIONS
- Hypersensitivity to econazole and other components that make up the drug;
- Children under 18 years.
Do not apply the product to areas with damaged skin.
PREGNANCY AND LACTATION
In pregnancy (I-II trimester) apply only if the intended benefit to the mother exceeds the potential risk to the fetus.
When prescribing the drug during lactation it is necessary to stop breastfeeding.
APPLICATION FOR CHILDREN
Contraindicated in children under 18 years.
SPECIAL INSTRUCTIONS
In patients with eczema, before the start of treatment it is necessary to conduct anti-extemal therapy. In the absence of the effect of the therapy in the recommended terms, it is necessary to verify the diagnosis. When the first symptoms appear
hypersensitivity drug should be discarded.
Avoid contact with eyes, mucous membranes, open wounds. If any of the side effects develop with the use of the drug, discontinue its continued use and consult a doctor.
Information on the possible effect of a medicinal product for medical use on the ability to drive vehicles, mechanisms
The drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
OVERDOSE
At casual reception of a cream inside there is a nausea, vomiting, a diarrhea.
Treatment: gastric lavage, ingestion of activated charcoal, symptomatic therapy.
DRUG INTERACTION
No data available.
TERMS OF RELEASE FROM PHARMACY
Without recipe.
TERMS AND CONDITIONS OF STORAGE
Store at temperatures not higher than 30 В° C. Do not freeze. Keep out of the reach of children. Shelf life - 3 years.
The information is provided for your information, do not self-medicate, it is dangerous for your health.
