Universal reference book for medicines
Product name: CEFECON ® H (CEFECON N)

Active substance: caffeine, naproxen, salicylamide

Type: NSAIDs with combined composition

Manufacturer: NIZHFARM (Russia)
Composition, form of production and packaging
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Suppositories rectal 1 supp.
naproxen 75 mg

caffeine 50 mg

salicylamide 600 mg

5 pieces.
- packings cellular planimetric (2) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2014.

PHARMACHOLOGIC EFFECT

Combined drug.
Has analgesic, antipyretic and anti-inflammatory effect.
Naproxen and salicylamide are NSAIDs whose mechanism of action is related to the inhibition of prostaglandin synthesis and the effect on the center of thermoregulation in the hypothalamus.

Caffeine has a psychostimulating, analeptic, spasmolytic effect on smooth muscles, reduces platelet aggregation and releases histamine from mast cells.

PHARMACOKINETICS

Data on the pharmacokinetics of Cefecon H are not available.

INDICATIONS

As an anesthetic for pain syndrome of mild and moderate severity:

- neuralgia;

- myalgia;

- sciatica;

- Lumbago;

- degenerative-dystrophic diseases of the musculoskeletal system (osteochondrosis, osteoarthrosis, ankylosing spondylitis);

- headache, migraine;

- toothache;

Primary algodismenorea.

As an antipyretic agent:

- febrile syndrome for cold, infectious and inflammatory diseases.

DOSING MODE

The drug should be used after cleansing enema or spontaneous bowel movement.

Assign 1 suppository 1-3 times / day.
The suppository is injected deep into the rectum, after which the patient must stay in bed for 30-40 minutes.
Duration of use as an anesthetic - no more than 5 days;
as an antipyretic agent - no more than 3 days.
SIDE EFFECT

From the side of the central nervous system: dizziness, agitation, drowsiness, noise in the ears, dizziness, slowing the speed of psychomotor reactions.

From the hemopoietic system: thrombocytopenia, granulocytopenia, aplastic anemia.

From the cardiovascular system: rarely - tachycardia, increased blood pressure.

Local reactions: itching and pain in the rectum.

Other: allergic reactions, violations of liver function, impaired renal function.

Side effects are mild and do not require discontinuation of therapy or any medical manipulation.

CONTRAINDICATIONS

- Stomach ulcer and duodenal ulcer in the phase of exacerbation;

bleeding;

- marked renal or hepatic insufficiency;

- arterial hypertension;

- organic diseases of the cardiovascular system;

- Chronic heart failure;

- increased excitability;

- Insomnia;

- an angle-closure glaucoma;

- bronchospasm (including caused by intake of NSAIDs);

- elderly age;

- children and adolescence under 16;

- Pregnancy;

- lactation (breastfeeding);

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

Cefekon N is contraindicated in pregnancy and lactation.

APPLICATION FOR FUNCTIONS OF THE LIVER

Contraindicated in severe renal failure.

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

Contraindicated in severe hepatic insufficiency.

APPLICATION FOR CHILDREN

The drug is contraindicated in children and adolescents under 16 years.

APPLICATION IN ELDERLY PATIENTS

The drug is contraindicated in elderly patients.

SPECIAL INSTRUCTIONS

When the itching and unpleasant sensations appear in the rectum, warm sunflower oil in the amount of 1 tablespoon in the form of an enema should be introduced into the rectum and the drug should be temporarily stopped.

OVERDOSE

Data on the overdose of Cefecon H are not available.

DRUG INTERACTION

With the simultaneous use of Cefexon H, the hypotensive effect of beta-adrenoblockers and ACE inhibitors decreases and the pharmacological effect of anticoagulants and sulfonylurea derivatives is enhanced.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored in a dry, cool, protected from light, out of reach of children.
Shelf life - 2 years.
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