Universal reference book for medicines
Product name: CHOPHYTOL

Active ingredient: Cynara

Type: Phytopreparation with choleretic and diuretic effect, reducing azotemia

Manufacturer: Laboratoires ROSA-PHYTOPHARMA (France)
Composition, form of production and packaging
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The tablets covered with a cover of brown color, round, biconcave.
1 tab.

dry water extract of fresh leaves of artichoke field 200 mg

Excipients: magnesium trisilicate - 12 mg, corn starch - 22 mg, talc - 3 mg, magnesium stearate - 3 mg.

The composition of the shell: gum mill - 1.152 mg, rosin - 1.152 mg, talc - 16.3 mg, gelatin - 0.384 mg, sucrose - 86.146 mg, calcium carbonate - 2.2 mg, colorant dispersant (sucrose, iron oxides of yellow, black and brown (E172), methyl parahydroxybenzoate (E218), ethylparahydroxybenzoate (E214)) 2.58 mg, carnauba wax 0.082 mg, polysorbate 80 0.004 mg.

12 pcs.
- blisters (5) - packs of cardboard.
30 pcs.
- blisters (2) - packs of cardboard.
30 pcs.
- blisters (6) - packs of cardboard.
60 pcs.
- polypropylene tubes (1) - cardboard packs.
180 pcs.
- polypropylene tubes (1) - cardboard packs.
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The solution for ingestion is dark brown in color, opaque, with a slight yellowish precipitate; a slight deposit may be present during storage.
100 ml

dense aqueous extract of fresh leaves of artichoke field 20 g

Auxiliary substances: ethanol - 2.8 g, orange flavoring - 2.8 g, glycerol - 0.18 g, methyl parahydroxybenzoate - 0.092 g, propyl parahydroxybenzoate - 0.046 g, purified water - up to 100 ml.

120 ml - bottles of dark glass (1) - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2015.

PHARMACHOLOGIC EFFECT

The preparation is of plant origin.
The pharmacological effect of the drug is caused by a complex of biologically active substances entering the leaves of the artichoke.Tsinarin in combination with phenolic acids has choleretic, as well as hepatoprotective effect. Contained in the artichoke ascorbic acid, carotene, vitamins B 1 and B 2, inulin promote the normalization of metabolic processes.
It also has a diuretic effect and enhances the excretion of urea.

PHARMACOKINETICS

The action of the drug Hofitol is the cumulative effect of its components, therefore, it is not possible to carry out kinetic observations;
all components can not be traced with the help of markers or bioassays. For the same reason, it is impossible to detect metabolites of the drug.
INDICATIONS

As part of complex therapy:

- dyskinesia of bile ducts by hypokinetic type;

- chronic non-calculous cholecystitis;

- chronic hepatitis;

- cirrhosis of the liver;

- chronic nephritis;

chronic renal failure.

DOSING MODE

Adults appoint 2-3 tables.
or 2.5-5 ml of the solution for oral administration 3 times / day before meals. The course of treatment is 2-3 weeks.
Children over 6 years of age are prescribed 1-2 tablets.
3 times / day before meals. The solution for oral administration, depending on the age, is prescribed in a dose ranging from 1/4 to 1/2 of the dose used in adults. The course of treatment is 2-3 weeks.
The doctor determines the need for repeated courses of therapy individually.

SIDE EFFECT

On the part of the digestive system: it is possible to develop diarrhea with prolonged intake of the drug in high doses.

Other: allergic reactions.

CONTRAINDICATIONS

- cholelithiasis;

- obstruction of the biliary tract;

- Acute liver, kidney, biliary and urinary tract diseases;

- Children's age to 6 years (for tablets);

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

The use of Hofitol during pregnancy and lactation (breastfeeding) is possible only under the supervision of a doctor.

APPLICATION FOR FUNCTIONS OF THE LIVER

Contraindicated in acute kidney disease.

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

Contraindicated use of the drug in the obstruction of the biliary tract, cholelithiasis, acute liver diseases and bile ducts.

APPLICATION FOR CHILDREN

Contraindicated in children under 6 years.

SPECIAL INSTRUCTIONS

1 teaspoon of the solution contains 0.13 g of ethyl alcohol.

OVERDOSE

Symptoms: may increase the manifestations of side effects.

DRUG INTERACTION

Drug interaction of the drug Hofitol is not described.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of the reach of children at a temperature of no higher than 25 ° C.
Shelf life of the tablets is 3 years; solution for oral administration - 4 years.
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