Universal reference book for medicines
Product name: HONDROGLYUXIDE (CHONDROGLUXID)

Active substance: chondroitin sulfate sodium, glucosamine

Type: A drug regulating the metabolism in cartilaginous tissue

Manufacturer: SYNTHESIS (Russia)
Composition, form of production and packaging
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The gel for external use is colorless or with a yellowish tinge, with a specific odor.
100 g

chondroitin sodium sulfate 5 g

glucosamine hydrochloride 2.5 g

Excipients: sodium disulfite - 0.05 g, ethanol 96% - 25 g, propylene glycol - 10 g, carbomer (carbopol) - 3 g, methyl parahydroxybenzoate - 0.2 g, lavender oil - 0.05 g, purified water - up to 100 g.

30 g - aluminum tubes (1) - cardboard packs.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2013.

PHARMACHOLOGIC EFFECT

A drug that regulates metabolism in the cartilaginous tissue (chondroprotector).
Stimulates regeneration of cartilaginous tissue, has anti-inflammatory and analgesic (analgesic) effect. Chondroitin sodium sulfate and glucosamine are involved in the synthesis of connective tissue, helping to prevent cartilage destruction processes and stimulating tissue regeneration.
Chondroitin sodium sulfate is an acidic mucopolysaccharide from cartilaginous tracheal tissue of cattle, a stimulator of repair of connective (including cartilaginous) tissue.
Stimulates the formation of the components of articular cartilage, the synthesis of proteoglycans and collagen type II, and also protects hyaluron from enzymatic cleavage (by suppressing the activity of hyaluronidase) and the damaging effect of free radicals. Chondroitin sodium sulfate maintains the viscosity of the synovial fluid, stimulates mechanisms of cartilage repair and inhibits the activity of those enzymes (elastase, hyaluronidase) that break down the cartilage. Chondroitin sodium sulfate in the treatment of osteoarthritis relieves the symptoms of this disease and reduces the need for NSAIDs.
Glucosamine has chondroprotective properties, takes part in the biosynthesis of proteoglycans and hyaluronic acid.
Glucosamine selectively acts on the articular cartilage, is a specific substrate and stimulator of the synthesis of hyaluronic acid and proteoglycans, inhibits the formation of peroxide radicals and enzymes that damage the cartilaginous tissue (collagenases and phospholipases).
PHARMACOKINETICS

Data on pharmacokinetics are not available.

INDICATIONS

- osteoarthritis of I-III stage (including joints and spine).

DOSING MODE

Outwardly.
The gel is applied 2-3 times / day with a thin layer of 4 cm strip (2 g) on ​​intact skin over the lesion site, then rubbed until absorbed for 2-3 minutes.Duration of the drug - 1 month. A repetition of the course is possible.
SIDE EFFECT

Allergic reactions are possible .

CONTRAINDICATIONS

- damage to the integrity of the skin at the site of application;

- children's age till 18 years;

- Pregnancy;

- lactation period;

- increased individual sensitivity to the components of the drug.

PREGNANCY AND LACTATION

During pregnancy and during breastfeeding the drug is not used.

APPLICATION FOR CHILDREN

Contraindicated at the age of 18 years.

SPECIAL INSTRUCTIONS

For external use only.
The drug should be applied only to undamaged skin areas, avoiding contact with open wounds, eyes and mucous membranes.
Impact on the ability to drive vehicles and manage mechanisms

The drug has no effect on the ability to drive vehicles, mechanisms and engage in other hazardous activities requiring special attention and quick reactions.

OVERDOSE

No data available.

DRUG INTERACTION

No data available.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored in a dry, protected from light, out of reach of children at a temperature of 15 ° to 25 ° C.
Do not freeze. Shelf life - 2 years.
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