Universal reference book for medicines
Name of the drug: CHLORHEXIDINE (CHLORHEXEDINE)

Active substance: chlorhexidine

Type: Antiseptic for topical application in gynecology

Manufacturer: BIOCHEMIK (Russia)
Composition, form of production and packaging
?
Vaginal suppositories 1 supp.
chlorhexidine bigluconate 16 mg

5 pieces.
- packings cellular planimetric (2) - packs cardboard.
?
Vaginal suppositories 1 supp.
chlorhexidine bigluconate 8 mg

5 pieces.
- packings cellular planimetric (2) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2010.

PHARMACHOLOGIC EFFECT

Chlorhexidine is an antiseptic drug for local (intravaginal) use, is active against the simplest, Gram-positive and Gram-negative bacteria, viruses, incl.
for Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gononhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex type 2. Some strains of Pseudomonas spp., Proteus spp., As well as acid-fast forms of bacteria, spores of bacteria are resistant to the drug. Chlorhexidine does not interfere with the functional activity of lactobacilli.
PHARMACOKINETICS

Systemic absorption with intravaginal application is insignificant.

INDICATIONS

- prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes and others);

- prevention of infectious and inflammatory complications in obstetrics and gynecology (before operative treatment of gynecological diseases, before childbirth and abortion, before and after installation of the intrauterine device (IUD), before and after diathermocoagulation of the cervix, before intrauterine studies);

- Treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, trichomonads).

DOSING MODE

Intravaginal.
Preliminarily releasing the suppository from the contour cell packaging, it is inserted into the vagina in the supine position on the back.
For treatment : 1 suppository 2 times / day for 7-10 days.
If necessary, it is possible to extend the course of treatment to 20 days.
For the prevention of sexually transmitted infections: 1 suppository not later than 2 hours after sexual intercourse.

SIDE EFFECT

Extremely rare (less than 0.1% of cases) are allergic reactions, itching of the skin, after the drug is withdrawn.

CONTRAINDICATIONS

- childhood;

- Hypersensitivity to the components of the drug.

With caution: pregnancy, lactation.

PREGNANCY AND LACTATION

The use of the drug during pregnancy and during lactation is possible if the intended benefit to the mother exceeds the potential risk to the fetus and the baby.

APPLICATION FOR CHILDREN

Contraindicated in childhood.

SPECIAL INSTRUCTIONS

Chlorhexidine retains activity (albeit somewhat lowered) in the presence of blood, pus.

OVERDOSE

At present, no cases of drug overdose have been reported.

DRUG INTERACTION

It is not recommended simultaneous use with iodine-containing drugs if they are administered intravaginally.

Chlorhexidine is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally.
The toilet of external sexual opganas does not affect the efficacy and tolerability of vaginal suppositories of Chlorhexidine. the drug is administered intravaginally.
TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

Keep the drug in a dark place at a temperature of no higher than 25 ° C.
Keep out of the reach of children.
Shelf life of the drug is 2 years.
Do not use after the expiration date.
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