Universal reference book for medicines
Product name: FERROVIR (FERROVIR)

Active substance: nonappropriate

Type: Antiviral and immunomodulating drug

Manufacturer: TECHNOMEDSERVICE ZAO FP (Russia)
Composition, form of production and packaging
The solution for the / m administration of 15 mg / ml is transparent, yellow, without foreign inclusions.
1 ml of 1 fl.
complex of sodium deoxyribonucleate with iron 15 mg 30 mg
2 ml - bottles (5) - packings of cellular contour (1) - packs cardboard.
The solution for the / m administration of 15 mg / ml is transparent, yellow, without foreign inclusions.
1 ml of 1 fl.
complex of sodium deoxyribonucleate with iron 15 mg 75 mg
5 ml - bottles (5) - packings of cellular contour (1) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2011.
PHARMACHOLOGIC EFFECT
An antiviral drug with a strong immunomodulatory effect of natural origin. It is a purified standardized complex salt of sodium deoxyribonucleate with iron.
It shows antiviral action against RNA and DNA-containing viruses. The drug activates antiviral, antifungal and antimicrobial immunity.
In the course of the use of Ferrovir in the complex therapy of HIV infection, there is an increase in the level of CD4 + lymphocytes in the blood (stored for 1-1.5 months after the end of the course of treatment). Simultaneously, the viral load in the body decreases, which is expressed in a decrease in the concentration of HIV RNA in comparison with the baseline level.
With recurrent herpetic infection, the duration of relapses decreases and long-term remission develops after a 10-day course of treatment.
The use of chronic hepatitis C leads to a decrease in the replicative activity of the hepatitis C virus and translates the process into a latent phase with the restoration of liver cells and the absence of viral replication, improves the tolerability of therapy (reducing nausea, dizziness).
The drug is characterized by a high degree of activity in the joint presence of primary and opportunistic viruses.
PHARMACOKINETICS
Suction
With the / m introduction quickly absorbed into the blood. The time to reach C max is 0.5 h.
Distribution
After 0.5 hours the concentration of the drug in the blood decreases due to its distribution in organs and tissues. It is distributed in organs and tissues with the participation of the endolymphatic pathway of transport; has a high tropism to the organs of the hematopoietic system; takes an active part in cellular metabolism, integrating into cellular structures. In the course of daily course use has the property of cumulating in organs and tissues.
Excretion
T 1/2 - 36 hours. Average retention time of the drug in organs and tissues is 72 hours. It is excreted from the body in unchanged form and in the form of metabolites, mainly with urine and partly with feces.
INDICATIONS
Ferrovir is used in combination therapy:
- chronic hepatitis C;
herpes;
- tick-borne encephalitis;
- viral opportunistic diseases in HIV-positive patients;
- HIV-infected patients and AIDS patients;
- HIV-infected patients with hepatitis C;
- HIV-infected patients with recurrent herpetic infection.
DOSING MODE
Adults in the treatment of HIV infection or AIDS drug is prescribed in / m 5 ml 2 times / day for 14 days. The following courses - according to the testimony.
When treating herpetic infection - in / m 5 ml 1-2 times / day for 10 days.
In the treatment of hepatitis C - in / m 5 ml 2 times / day for 14 days. In the next 14 days - in the same daily dose every other day.
In the treatment of tick-borne encephalitis - 5 ml of solution 2 times / day for 5-10 days.
SIDE EFFECT
Possible: fever, hyperemia, moderate soreness at the injection site.
CONTRAINDICATIONS
- Pregnancy;
- lactation (breastfeeding);
- childhood;
- Hypersensitivity to the drug.
PREGNANCY AND LACTATION
The drug is contraindicated for use in pregnancy and lactation (breastfeeding).
APPLICATION FOR CHILDREN
Contraindication: children's age.
SPECIAL INSTRUCTIONS
To reduce pain, the drug should be injected / m slowly for 1-2 minutes.
In / in the introduction of the drug is not allowed.
The results of clinical studies allow us to recommend the use of the drug Ferrovir in the treatment of cytomegalovirus infection, papillomavirus infection, cytomegalovirus infection and HSV.
The efficacy in both combined and in monotherapy of herpetic infection has been proven with a single daily administration of the drug within 10 days. When treating papillomavirus infection - 5 ml 1 time / day in / m with an interval of 72 hours. In the treatment of cytomegalovirus infection - 5 ml 1-2 times / day for 10 days.
OVERDOSE
At present, no cases of an overdose of Ferrovir have been reported.
DRUG INTERACTION
The drug moderately potentiates the effect of anticoagulants, hepatoprotectors. When used in complex therapy reduces the toxicity and negative impact of concomitant medications (headache, nausea).
TERMS OF RELEASE FROM PHARMACY
The drug is released by prescription.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored in a dark place at a temperature of 4 ° to 20 ° C. Shelf life - 5 years.
Solution for injection should be used immediately after opening the vial; Do not store opened bottles.
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