Universal reference book for medicines
Product name: FAMOSAN ® (FAMOSAN ® )

Active ingredient: famotidine

Type: The blocker of histamine H 2 -receptors.
Antiulcer drug
Manufacturer: PRO.MED.CS Praha (Czech Republic)
Composition, form of production and packaging
Tablets covered with a coat of
brownish-pink color, lenticular-shaped with a smooth surface;
on the fracture - a core of white or almost white color, homogeneous in structure.
1 tab.

famotidine 20 mg

Excipients: microcrystalline granulated cellulose, granulated lactose, corn starch, magnesium stearate, silicon colloidal dioxide, hypromellose, titanium dioxide, macrogol 6000, iron oxide red, iron oxide yellow, emetic dimethicone.

10 pieces.
- packings cellular planimetric (2) - packs cardboard.
Tablets covered with a coat of brownish-yellow color, lenticular, with a smooth surface;
on the fracture - a core of white or almost white color, homogeneous in structure.
1 tab.

famotidine 40 mg

Excipients: microcrystalline granulated cellulose, granulated lactose, corn starch, magnesium stearate, silicon colloidal dioxide, hypromellose, titanium dioxide, macrogol 6000, iron oxide red, iron oxide yellow, emetic dimethicone.

10 pieces.
- blisters (1) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.

The product description was approved by the manufacturer for the 2009 print edition.

PHARMACHOLOGIC EFFECT

The blocker of histamine H 2 -receptors.
It causes a dose-dependent suppression of hydrochloric acid production and a decrease in pepsin activity, which creates optimal conditions for cicatrization of the ulcer. Suppresses basal and stimulated secretion of hydrochloric acid in the stomach by more than 80-90% - after 2 hours, after 6 hours - by 70-75%, after 10 hours - by 40-45%. It does not significantly alter the level of gastrin in the plasma. The duration of the drug in a single dose depends on the dose and is from 12 to 14 hours.
INDICATIONS

- Stomach ulcer and duodenal ulcer in the phase of exacerbation, prevention of relapses;

- symptomatic (stress ulcers, iatrogenic) ulcers;

- chronic pancreatitis in the phase of exacerbation;

- functional dyspepsia associated with increased secretory function of the stomach;

- erosive esophagitis, reflux esophagitis;

- Prevention of bleeding from the upper gastrointestinal tract;

- Zollinger-Ellison syndrome.

DOSING MODE

With gastric ulcer and duodenal ulcer usually appoint 20 mg 2 times / day or 40 mg 1 time / day at night.
If necessary, the daily dose can be increased to 80-160 mg.
To prevent recurrence appoint 20 mg 1 time / day before bedtime.

Tablets of Famosana should be swallowed without sniffing, squeezed with enough water.

SIDE EFFECT

On the part of the digestive system: dry mouth, nausea, vomiting, flatulence, constipation, diarrhea, anorexia, increased activity of liver enzymes.

From the side of the central nervous system: headache, dizziness, fatigue, drowsiness.

On the part of laboratory indicators: an increase in the level of urea, leukopenia, thrombocytopenia.

Other: very rarely - skin rash, menstrual irregularity.

CONTRAINDICATIONS

- Pregnancy;

- lactation;

- Hypersensitivity to famotidine and other blockers of histamine H 2 -receptors.

PREGNANCY AND LACTATION

Contraindicated in pregnancy and lactation.

APPLICATION FOR FUNCTIONS OF THE LIVER

In chronic renal failure, a dose adjustment is required.

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

Caution is necessary to prescribe the drug to patients with impaired liver function


SPECIAL INSTRUCTIONS

Before starting therapy with histamine H2 receptor blockers, a histological examination is necessary in order to exclude the malignant nature of the disease.

In chronic renal failure, a dose adjustment is required.
Also, care should be taken to prescribe the drug to patients with impaired liver function.
DRUG INTERACTION

With simultaneous use with antacid agents containing magnesium and aluminum, the intensity of absorption of Famosan decreases, therefore, the interval between taking these drugs should be at least 1-2 hours.

TERMS OF RELEASE FROM PHARMACY

The drug is released by prescription.

TERMS AND CONDITIONS OF STORAGE

List B. In a dry, protected from light and out of reach of children, at a temperature of 15-25 ° C.
Shelf life - 4 years.
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