Universal reference book for medicines
Name of the drug: FIBRINOLYSIN (FIBRINOLYSIN)

Active substance: fibrinolysin (human)

Type: Thrombolytic - tissue plasminogen activator

Producer: NGO MIKROGEN (Russia)
Description of the active substance:
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..

PHARMACHOLOGIC EFFECT
Fibrinolytic agent.
The physiological component of the natural anticoagulant system. Has a direct fibrinolytic effect. Stimulates both tissue fibrinolysis (thrombus dissolution) and systemic fibrinolysis (destruction of fibrinogen), resulting in its use can lead to hypofibrinogenemia and bleeding. In the appointment of fibrinolysin, the lysis of the fibrin clot is carried out from the outside, since the agent is unable to penetrate into the organized thrombus.
INDICATIONS
Thromboembolism of the pulmonary artery, thromboembolism of cerebral vessels, myocardial infarction, acute thrombophlebitis, exacerbation of chronic thrombophlebitis.

DOSING MODE
In / in (drip) in a 0.9% solution of sodium chloride (100-160 units per 1 ml of solution) with the addition of heparin (at a rate of 10 thousand ED for every 20,000 fibrinolysin).
The daily dose of fibrinolysin is up to 20-40 thousand AD. The duration of administration is 3-4 hours.
SIDE EFFECT
Allergic reactions, bleeding are possible.

CONTRAINDICATIONS
Hemorrhagic diathesis, bleeding, open wounds, peptic ulcer of the stomach and duodenum, nephritis, hypofibrinogenemia, tuberculosis (acute form), radiation sickness, hypersensitivity to fibrinolysin.

APPLICATION FOR FUNCTIONS OF THE LIVER
Contraindicated in nephritis.

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