Universal reference book for medicines
Name of the preparation: TELECTOL

Active substance: vinpocetine

Type: A drug that improves blood circulation and brain metabolism

Manufacturer: ФП ОБОЛЕНСКОЕ (Russia)
Composition, form of production and packaging
The tablets covered with a cover of
blue color, round, biconcave.

1 tab.

vinpocetine 5 mg

- "- 10 mg

[PRING] pregelatinized starch, lactose, copolyvidone, microcrystalline cellulose, magnesium stearate, talc, silicon dioxide colloid (aerosil), hypromellose, macrogol, titanium dioxide, dye blue.

10 pieces.
- packings of cellular contour (1) - packs cardboard.
10 pieces.
- packings cellular planimetric (2) - packs cardboard.
10 pieces.
- packings cellular planimetric (3) - packs cardboard.
10 pieces.
- packings cellular planimetric (5) - packs cardboard.
10 pieces.
- packings cellular planimetric (10) - packs cardboard.
20 pcs.
- packings of cellular contour (1) - packs cardboard.
20 pcs.
- packings cellular planimetric (2) - packs cardboard.
20 pcs.
- packings cellular planimetric (3) - packs cardboard.
20 pcs.
- packings cellular planimetric (5) - packs cardboard.
20 pcs.
- packings cellular planimetric (10) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.

The product description was approved by the manufacturer for the 2009 print edition.

PHARMACHOLOGIC EFFECT

A drug that improves blood circulation and brain metabolism.
Has vasodilator, antihypoxic and antiplatelet effect.
The mechanism of action is associated with inhibition of phosphodiesterase.
This leads to an increase in the content of cAMP in the cells, which in turn causes a decrease in the calcium content in the cytoplasm of smooth muscle cells and the relaxation of myofibrils.
It dilates the blood vessels of the brain, increases blood flow, mainly in the ischemic areas, improves the supply of oxygen to the brain.
Promotes the utilization of glucose and increases the level of catecholamines in the central nervous system, stimulates the metabolism of norepinephrine and serotonin in the brain tissues.Reduces platelet aggregation, blood viscosity, promotes increased erythrocyte deformability and normalization of venous outflow against a background of decreased resistance of cerebral vessels. Systemic blood pressure decreases slightly.
Teletext is effective in the acute period of stroke: it accelerates the regress of cerebral and focal neurological symptoms, improves memory, attention, intellectual productivity.

In the elderly and senile age, the sensitivity of cerebral vessels to the relaxing action of vinpocetin increases, which is due to the sensitization of the adenylate cyclase-cAMP system during aging.

PHARMACOKINETICS

Suction

After taking the medication, vinpocetine is rapidly absorbed from the digestive tract.
Bioavailability is about 60%. C max is achieved after 1 hour. Easily penetrates through the histogematic barriers (including through the BBB) and penetrates into the tissues.
Excretion

T 1/2 is about 5 hours.

INDICATIONS

- acute (after completion of the course of parenteral administration of vinpocetine, and also when parenteral administration is not possible) and chronic forms of cerebral circulatory insufficiency (including acute and residual stages of stroke, transient ischemic attacks, encephalopathies, multi-infarct dementia);

- vascular diseases of the retina and / or choroid of the eye (due to atherosclerosis, angiospasm, thrombosis);

- degenerative changes in the yellow spot of the eye caused by atherosclerosis or angiospasm;

- secondary glaucoma (due to vascular obturation);

- age-related vascular or toxic (medicamentous) hearing impairment;

- Ménière's disease;

dizziness of labyrinth origin;

- vegetative manifestations of climacteric syndrome.

DOSING MODE

The drug should be taken orally 5-10 mg 3 times / day for 2 months.
Before cancellation of the drug should gradually reduce the dose.
Possible repeated courses 2-3 times a year.

SIDE EFFECT

From the cardiovascular system: a decrease in blood pressure, tachycardia, extrasystole, slowing of intraventricular conduction.

CONTRAINDICATIONS

- severe cardiac rhythm disturbances;

- IHD (severe course);

- acute stage of hemorrhagic stroke;

- Pregnancy;

- lactation period (breastfeeding);

- Hypersensitivity to the drug.

PREGNANCY AND LACTATION

The drug is contraindicated for use in pregnancy and lactation (breastfeeding).

OVERDOSE

Treatment: with an overdose - gastric lavage, taking activated charcoal, symptomatic therapy.

DRUG INTERACTION

When using TeleTotal on a background of heparin therapy, the risk of hemorrhagic complications increases.

TERMS OF RELEASE FROM PHARMACY

The drug is released by prescription.

TERMS AND CONDITIONS OF STORAGE

List B. The drug should be stored out of reach of children, dry, protected from light at a temperature of no higher than 25 ° C.
Shelf life - 2 years.
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