Universal reference book for medicines
Product name: TANAKAN ® (TANAKAN ® )

Active substance: Ginkgo biloba

Type: Phytopreparation, improving cerebral and peripheral blood circulation

Manufacturer: IPSEN PHARMA (France) manufactured by BEAUFOUR IPSEN INDUSTRIE (France)
Composition, form of production and packaging
The tablets covered with a film membrane brick-red color, round, biconcave; On a break of light brown color, with a specific smell.
1 tab.

ginkgo bilobate leaf extract (EGb 761 ® ) 40 mg,

in t.ch.
flavonol glycosides 22-26.4%
ginkgolides-bilobalides 5.4-6.6%


The composition of the nucleus: lactose monohydrate - 82.5 mg, microcrystalline cellulose - 50 mg, corn starch - 37 mg, silicon dioxide colloid - 28 mg, talc - 11.25 mg, magnesium stearate - 1.25 mg.

Sheath composition: hypromellose (E464) - 6 mg, macrogol 400 - 1.5 mg, macrogol 6000 - 1.5 mg, titanium dioxide (E171) - 1 mg, iron oxide red (E172) - 0.7 mg.

15 pcs.
- blisters (2) - packs of cardboard.
15 pcs.
- blisters (6) - packs of cardboard.
The solution for ingestion is brownish-orange in color, with a characteristic odor.
100 ml

ginkgo bilobate leaf extract (EGb 761 ® ) 4 g,

in t.ch.
flavonol glycosides 24%
ginkgolides-bilobalides 6%

[PRING] sodium saccharinate - 500 mg, flavoring orange - 0.75 ml, flavoring lemon - 0.75 mg, ethanol 96% - 59 ml, purified water - up to 100 ml.

30 ml - bottles of dark glass (1) complete with a pipette-dispenser (with a capacity of 1 ml) - packs of cardboard.


Description of the drug approved by the manufacturer for the printed edition of 2015.


Angioprotective agent of plant origin.
Standardized and titrated preparation of plant origin, the effect of which is due to the influence on metabolic processes in cells, rheological properties of blood, as well as vasomotor reactions of blood vessels.
The drug improves the supply of the brain with oxygen and glucose.
Normalizes the tone of arteries and veins, improves microcirculation. Helps improve blood flow, prevents the aggregation of red blood cells. Has a retarding effect on the platelet activation factor.
It improves metabolic processes, has antihypoxic effect on tissues.
Prevents formation of free radicals and peroxide oxidation of cell membrane lipids. Affects the release, reverse capture and catabolism of neurotransmitters (norepinephrine, acetylcholine, dopamine, serotonin) and their ability to bind to membrane receptors.

Ginkgolides A and B and bilobalides have a bioavailability of 80% to 90% when taken orally.
C max is achieved in 1-2 hours; T 1/2 is from 4 hours (ginkgolid A and bilobalid) to 10 h (ginkgolid B). The main way of excretion is the kidneys.

- Cognitive and sensorine deficiency of various genesis (with the exception of Alzheimer's disease and dementia of various etiologies);

- Intermittent claudication in chronic obliterating arteriopathies of the lower extremities (2 degrees Fontaine);

- impaired vision of vascular genesis, a decrease in its severity;

- Hearing impairment, tinnitus, dizziness and coordination disorders of predominantly vascular genesis;

- Raynaud's disease and syndrome.


Assign adults inside by 40 mg (1 tablet or 1 ml solution for ingestion) 3 times / day during meals.

A tablet should be washed down with half a glass of water.

The solution for oral administration should be dissolved in half a glass of water.
When taking the drug in the form of a solution for oral administration, use the supplied pipette-dispenser (1 dose = 1 ml of solution).
The minimum course of treatment is at least 3 months.
An increase in the duration and conduct of repeated courses of treatment is possible on the recommendation of a doctor.

Allergic reactions: redness, skin rash, swelling, itching, urticaria.

From the coagulating system of blood: a decrease in blood clotting and the possibility of bleeding (with prolonged use).

Dermatological reactions: eczema.

From the side of the central nervous system: headache, dizziness, tinnitus.

From the digestive system: nausea, vomiting, abdominal pain, dyspepsia, diarrhea.

In case of adverse reactions, the patient should stop taking the drug and consult a doctor.


- erosive gastritis in the phase of exacerbation;

- Stomach ulcer and duodenal ulcer in the phase of exacerbation;

acute disorders of cerebral circulation;

acute myocardial infarction;

- decreased blood coagulability;

- congenital galactosemia, lactase deficiency, lactose intolerance, glucose / galactose malabsorption syndrome (for tablets);

- children and adolescence under 18;

- Pregnancy;

- the period of lactation (breastfeeding);

- Hypersensitivity to any of the components of the drug.

Caution should be given to patients with alcoholism, liver disease, craniocerebral trauma and brain diseases, since the drug in the form of a solution contains 450 mg of ethyl alcohol per dose (1 dose).


Tanakan ® is contraindicated in pregnancy and lactation (breastfeeding) due to the lack of clinical data on the use of the drug in this group of patients.


Caution should be given to patients with liver disease


Contraindicated in children under 18 years of age.


Before using the drug, you need to consult a doctor.

Improvement of the condition manifests itself 1 month after the start of treatment.

In one single dose of oral solution contains 450 mg of ethyl alcohol (57% v / v), in the maximum daily dose of 1.35 g of ethyl alcohol.

Impact on the ability to drive vehicles and manage mechanisms

the period of taking the drug is not recommended to carry out potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions (including the management of vehicles, work with moving mechanisms), because the drug may cause dizziness and the solution contains ethyl alcohol.

Currently, no cases of overdose have been registered.


In clinical studies with EGb 761, both inhibition and induction of cytochrome P450 isoenzymes were detected.
With the simultaneous administration of EGb 761 with midazolam, the level of the latter changed presumably because of the effect on CYP3A4. Therefore, caution should be exercised in the joint administration of EGb 761 and drugs metabolized by the CYP3A4 isoenzyme and having a low therapeutic index.
Do not apply the drug to patients systematically receiving acetylsalicylic acid (as an antiplatelet agent), anticoagulants (direct and indirect action), and other drugs that reduce blood clotting.

With the simultaneous use of Tanakan in the form of a solution for oral administration with antibiotics, the cephalosporin group (cefamandol, cefoperazone, latamoxef), gentamicin, chloramphenicol, disulfiram, thiazide diuretics, anticonvulsants, oral hypoglycemic drugs (chlorpropamide, glibenclamide, glipizide, tolbutamide, metformin lactacidosis)), antifungal agents (griseofulvin), 5-nitroimidazole derivatives (metronidazole, ornidazole, secnidazole, tinidazole), ketoconazole, cytos
tatics (procarbazine), tricyclic antidepressants, tranquilizers may cause such reactions as hyperthermia, skin flushing, vomiting, heart palpitations, since 1 dose of Tanakan in the form of oral solution contains 450 mg of ethyl alcohol.

The drug is approved for use as a means of OTC.


The drug should be stored out of the reach of children at a temperature of no higher than 25 ° C.
Shelf life - 3 years.
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