Universal reference book for medicines
Name of the preparation: SANORIN WITH EQUALIPE OIL (SANORIN WITH EUCALIPTUM OLEUM)

Active substance: naphazoline

Type: Vasoconstrictive drug for topical application in ENT practice

Manufacturer: Teva Pharmaceutical Industries (Israel) manufactured by TEVA Czech Industries (Czech Republic)
Composition, form of production and packaging
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Nasal drops 0.1% in the form of a white, easily shaking emulsion.
1 ml of 1 fl.

naphazoline nitrate 1 mg 10 mg

[PRING] ethylenediamine, boric acid, cetyl alcohol, methylparaben, eucalyptus oil, polysorbate 80, cholesterol, liquid paraffin, purified water.

10 ml - bottles of dark glass (1) with a dropper "SANO" and a lid - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2012.

PHARMACHOLOGIC EFFECT

Alpha 2- adrenomimetic.
When topical application has a rapid, pronounced and prolonged vasoconstrictive effect on the vessels of the mucous membrane (reduces swelling, flushing, exudation). Relieves nasal breathing in rhinitis. After 5-7 days of use there is tolerance.
PHARMACOKINETICS

Data on the pharmacokinetics of the drug Sanorin and eucalyptus oil are not available.

INDICATIONS

- Acute rhinitis;

- sinusitis;

- Eustachyte;

- laryngitis;

- to facilitate the conduct of a rhinoscopy;

- the need to stop nasal bleeding.

DOSING MODE

Adults appoint 1-3 drops in each nasal passage 2-3 times / day.
Apply for a short time, not more than 1 week. If nasal breathing is facilitated, then the use of Sanorin with eucalyptus oil can be completed earlier. Repeated use of the drug is possible in a few days.
Shake the bottle before use.
An open vial of the drug can be used for 4 weeks.
SIDE EFFECT

From the side of the digestive system: nausea.

From the cardiovascular system: tachycardia, increased blood pressure.

From the side of the central nervous system: headache, irritability.

Allergic reactions: rash.

Local reactions: reactive hyperemia, swelling of the nasal mucosa;
when applied for more than 1 week - irritation, in some cases - swelling of the nasal mucosa.
CONTRAINDICATIONS

- chronic rhinitis;

- arterial hypertension;

- severe atherosclerosis;

- tachycardia;

- thyrotoxicosis;

- diabetes;

- simultaneous administration of MAO inhibitors and a period of up to 14 days after the end of their use;

- children's age till 15 years;

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

Data on the safety of the drug during pregnancy and lactation (breastfeeding) are not provided.

APPLICATION FOR CHILDREN

Contraindication: children under 15 years.

SPECIAL INSTRUCTIONS

With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and therefore it is recommended after 5-7 days of use in adults to take a break for several days.

The drug may have a resorptive effect.

The doctor determines the need for Sanorin with eucalyptus oil with other medicines individually.

OVERDOSE

Symptoms: prolonged or frequent administration of Sanorin with eucalyptus oil in the nasal cavity can cause swelling of the nasal mucosa and sensation of its congestion.
The risk of overdose (especially if swallowed) occurs in younger children and may cause CNS depression, which is manifested by drowsiness, lowering of body temperature, increased sweating, slowing of heart rate, increased blood pressure or its subsequent decrease, extremely rarely coma .
Treatment: symptomatic therapy.

DRUG INTERACTION

Simultaneous administration with MAO inhibitors and a period of up to 14 days after the end of their use, increases the risk of development of severe arterial hypertension (release of deposited catecholamines under the action of nafazoline).

Slows the absorption of local anesthetics.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children, protected from light at a temperature of 10 ° to 25 ° C.
Shelf life - 4 years.
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