Universal reference book for medicines
Product name: SANGVIRITRIN (SANGUIRITRIN)

Active substance: nonappropriate

Type: Phytomedication with antimicrobial effect

Manufacturer: ФАРМЦЕНТР ВИЛАР (Russia)
Composition, form of production and packaging
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Tablets coated with an enteric coating of dark orange to brownish-orange color, round in shape with biconvex surfaces.
1 tab.

sanguirythrin (sanguinarine hydrogen sulfate and chelerythrine hydrogensulfate) 5 mg

[PRING] sucrose (sugar or sugar refined sugar), povidone low molecular weight (polyvinylpyrrolidone low molecular weight medical 12600 ± 2700), magnesium stearate.

Sheath composition: opedrai II white OY-LS-28911 (hydroxypropylmethylcellulose (hypromellose), lactose monohydrate, polydextrose, polyethylene glycol 4000 (macrogol 4000), titanium dioxide dye), acrylate white 93О18359 (copolymer of methacrylic acid with ethyl acrylate 1: 1, titanium dye dioxide, talc, triethyl citrate, silicon dioxide colloidal anhydrous, sodium hydrogen carbonate, sodium lauryl sulfate), opadrai II red 85F25163 (hydroxypropylmethylcellulose (hypromellose), lactose monohydrate or polydextrose, polyethylene glycol 4000 (macrogol 4000), dye yell
for oxide red (E172)).
10 pieces.
- packings of cellular contour (1) - packs cardboard.
10 pieces.
- packings cellular planimetric (3) - packs cardboard.
10 pieces.
- packings cellular planimetric (5) - packs cardboard.
30 pcs.
- packings of cellular contour (1) - packs cardboard.
50 pcs.
- packings of cellular contour (1) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2014.

PHARMACHOLOGIC EFFECT

Sanguirythrin is derived from the Macleaya cordata (Willd.) R.Br. grass and Macleaya microcarpa (Maxim.) Fedde) of the poppy family - Papaveraceae.
Sangviritrin is a mixture of bisulfates of two quarantine benzophenanthridine alkaloids of similar structure and properties, sanguinarine and chelerythrine.
The drug has a wide spectrum of antimicrobial activity, acting on Gram-positive and Gram-negative bacteria, pathogenic fungi, yeast-like fungi of the genus Candida, including multiresistant strains of microorganisms, as well as actinomycetes and some pathogenic protozoa.
At the core of the mechanism of antimicrobial action of the drug is the suppression of bacterial nuclease, a violation of the permeability of cell walls. The drug also has a weak anticholinesterase action.
INDICATIONS

In the complex therapy of acute and chronic purulent-inflammatory diseases:

- Acute intestinal infections (dysentery, salmonellosis, food poisoning);

- wound infections and various infectious complications caused by pathogenic microflora (convalescent bacteriocarrier);

- diseases associated with the violation of normal microflora (dysbiosis);

- diseases caused by pathogenic fungi (pharyngicosis, candidiasis, microsporia).

DOSING MODE

Tablets are taken orally (without chewing!) After eating.

Adults usually appoint 2 (10 mg) tablets 3-4 times a day (if necessary, the daily dose can be increased to 9 tablets).

Children 10-15 years old are prescribed 1-2 (5 - 10 mg) tablets 3 times a day (maximum daily dose - up to 6 tablets).

Children 5-10 years - 1 tablet (5 mg) 3-4 times a day (maximum daily dose - up to 4 tablets).

Children 3-5 years - 1 tablet (5 mg) 2-3 times a day (the maximum daily dose is up to 3 tablets).

The duration of treatment depends on the nosological form and severity of the disease and is, on average:

- with acute intestinal infections (dysentery, salmonellosis, food toxic infections) - 5-7 days (if necessary, up to 10 days);

- with dysbacteriosis - up to 10-14 days;

- with bacteriocarrier (bacterial release) - 7-14 days;

- with pharyngomycosis and candidiasis - up to 14 days;

- with microsporia - 4-5 weeks.

Conducting repeated courses of treatment is possible on the recommendation of a doctor.

SIDE EFFECT

There may be allergic reactions.
When chewing the tablets, dyspeptic phenomena (nausea, vomiting), abdominal pains are possible.
CONTRAINDICATIONS

- hypersensitivity to the components of the drug;

- epilepsy;

- hyperkinesis;

- bronchial asthma;

- cardiac ischemia;

- severe liver and kidney disease with impaired function;

- Children's age up to 3 years.

PREGNANCY AND LACTATION

The use of the drug during pregnancy and during breastfeeding is possible in view of the expected benefits for the mother and the potential risk to the fetus / child.
It is necessary to consult a doctor.
APPLICATION FOR FUNCTIONS OF THE LIVER

Contraindicated in severe kidney disease with impaired function.

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

Contraindicated in severe liver disease with impaired function.

APPLICATION FOR CHILDREN

Contraindicated for children under 3 years.

SPECIAL INSTRUCTIONS

Information for patients with diabetes mellitus: In a single dose, the drug contains 93.7 mg of sugar (sucrose) or sugar-refined sugar, which corresponds to 0.008 XE.

OVERDOSE

In case of an overdose of the drug, nausea, vomiting, abdominal pain, dizziness, headache are possible.

In case of an overdose, a gastric lavage should be performed.
Treatment is symptomatic.
DRUG INTERACTION

Not described.

TERMS OF RELEASE FROM PHARMACY

Without recipe.

TERMS AND CONDITIONS OF STORAGE

List B. In a dry, the dark place at a temperature of no higher than 25 ° C.
Keep out of the reach of children. Shelf life - 3 years.
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