Universal reference book for medicines
Product name: REGULAX PICOSULFATE (REGULAX PICOSULFATE)

Active substance: sodium picosulfate

Type: Laxative drug that stimulates intestinal motility

Manufacturer: KREWEL MEUSELBACH (Germany)

Composition, form of production and packaging
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Drops for ingestion 1 ml (15 drops)
sodium picosulphate 7.5 mg

10 ml - a bottle of a dropper of dark glass (1) - packs cardboard.

20 ml - a bottle of a dropper of dark glass (1) - packs cardboard.

50 ml - a bottle of a dropper of dark glass (1) - packs cardboard.

INSTRUCTION FOR THE SPECIALIST.

The product description was approved by the manufacturer for the 2009 print edition.

PHARMACHOLOGIC EFFECT

Laxative.
The active form of the preparation, formed by hydrolysis under the influence of intestinal microorganisms, directly excites the nerve structures of the intestinal wall, as a result of which the movement of intestinal contents accelerates, the absorption of electrolytes and water decreases. The action occurs 10-12 hours after admission.
PHARMACOKINETICS

After oral administration, it is not absorbed from the digestive tract and does not undergo hepatic intestinal circulation.

INDICATIONS

- Atonic constipation;

- regulation of the stool (hemorrhoids, proctitis, anus fractures);

- preparation for surgical operations, instrumental and roentgenological studies.

DOSING MODE

Inside, before bed.
Depending on the effect obtained, the dose in subsequent administration is increased or decreased. Adults: the initial dose - 13 drops, withpersistent constipation - up to 26 drops. For children older than 4 years, the initial dose is 5-8 drops. The course of treatment is 7 days.
SIDE EFFECT

Possible: diarrhea, abdominal pain, bloating, dehydration, water-electrolyte balance disorders, weakness, convulsions, lowering blood pressure.

CONTRAINDICATIONS

- intestinal obstruction;

- strangulated hernia;

- acute inflammatory diseases of the abdominal cavity;

- peritonitis;

- Abdominal pain (of unknown origin);

bleeding from the gastrointestinal tract;

- Metrorrhagia;

- Cystitis;

- severe dehydration;

- Spastic constipation;

- Children's age (up to 4 years);

- Pregnancy (I trimester);

- Hypersensitivity to the drug.

With care - the period of lactation.

PREGNANCY AND LACTATION

Contraindicated in the first trimester of pregnancy.
Multiple administration of the drug during the II and III trimesters should be carried out only after a thorough assessment of the need and risks, since there is insufficient information about the use of the drug in pregnancy.
With care - the period of lactation.

APPLICATION FOR CHILDREN

Contraindicated in children under 4 years.
For children older than 4 years, the initial dose is 5-8 drops. The course of treatment is 7 days.
SPECIAL INSTRUCTIONS

Do not take without medical supervision for more than 7 days.
Long-term administration often leads to increased intestinal fixation.
Children should be used only in consultation with a doctor.

Suitable for diabetics;
contains sugar substitutes; 1 ml corresponds to 0.03 XE.
OVERDOSE

Symptoms: with a chronic overdose it is possible to develop ischemia of the mucous membrane of the colon, secondary hyperaldosteronism, urolithiasis, and damage to the renal tubules.

Treatment: gastric lavage, correction of water-electrolyte balance disorders, antispasmodics.

DRUG INTERACTION

Perhaps increased sensitivity to cardiac glycosides.

Glucocorticosteroids, diuretics increase the risk of electrolyte disorders.

Antibiotics of a wide spectrum of action reduce a laxative effect.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

Store at temperatures between 15 ° C and 25 ° C, out of the reach of children.
Shelf life - 5 years.
Shelf life after bottle opening is 6 months.
Do not use after the expiry date printed on the package.
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