Composition, form of production and packaging
? Tablets are white, round, flat, with cut edges and a separating groove.
1 tab.
metamizole 500 mg
pituophenone hydrochloride 5 mg
fenpiverinia bromide 100 Ојg
[PRING] starch, lactose, microcrystalline cellulose, silicon dioxide colloid, magnesium stearate, talc.
10 pieces. - Strips (1) - packs of cardboard.
20 pcs. - Strips (1) - packs of cardboard.
20 pcs. - Strips (5) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.
The product description was approved by the manufacturer for the 2009 print edition.
PHARMACHOLOGIC EFFECT
Spasmoanalgesic. The composition of the drug includes non-narcotic analgesic metamizole sodium (analgin), myotropic antispasmodic drug pituophenone hydrochloride and anticholinergic agent fenpiverinia bromide.
Metamizole is a derivative of pyrazolone. It has analgesic, antipyretic and anti-inflammatory action.
Pitophenone, like papaverine, has a direct myotropic effect on the smooth muscles of the internal organs and causes it to relax.
Fenpierinium due to anticholinergic action has an additional relaxing effect on smooth muscle.
The combination of the three components of the drug leads to a mutual enhancement of their pharmacological action, expressed in relieving the pain, relaxing the smooth muscles, reducing the fever.
INDICATIONS
- mild or moderate pain syndrome with spasms of smooth muscles of internal organs - renal and biliary colic, intestinal spasms, dysmenorrhea and other spastic conditions of internal organs;
- for short-term symptomatic treatment for headaches, migraine pain, joint pain, neuralgia, ischialgia, myalgia;
- as an adjuvant can be used to reduce pain after surgical and diagnostic interventions;
- to reduce high fever with colds and infectious and inflammatory diseases.
DOSING MODE
Adults and adolescents over 15 years are prescribed inside (preferably after eating) 1-2 tablets 2-3 times / day. The daily dose should not exceed 6 tab. Duration of reception no more than 5 days.
An increase in the daily dose of the drug or the duration of treatment is possible only under the supervision of a physician.
In children, the drug is used only as directed by a doctor. Dosage for children 6-8 years -1/2 tablets; for children 9-12 years old - 3/4 tablets; for children 13-15 years - 1 tablet; multiplicity of appointment - 2-3 times / day.
Other dosage regimens are possible only after consultation with a physician.
SIDE EFFECT
In therapeutic doses, the drug is usually well tolerated.
Sometimes allergic reactions are possible (skin rash, itching, very rarely anaphylactic shock).
In rare cases - a burning sensation in the epigastric region, dry mouth, headache.
Possible dizziness, lowering blood pressure, tachycardia, cyanosis.
With long-term admission - cases of violation of the blood system (thrombocytopenia, leukopenia, agranulocytosis).
With propensity to bronchospasm may provoke an attack.
All side effects should be reported to your doctor.
CONTRAINDICATIONS
- marked violations of the liver or kidney;
- genetic absence of glucose-6-phosphate dehydrogenase;
- Tachyarrhythmia;
- the closed-angle form of glaucoma;
- hypertrophy of the prostate with a tendency to urinary retention;
- gastrointestinal obstruction;
- megacolon;
- diseases of the blood system;
- Collaptoid states;
- I trimester and the last 6 weeks of pregnancy;
- lactation period;
- Hypersensitivity to pyrazolone derivatives and other components of the drug.
Tablets are not used for children under 5 years.
PREGNANCY AND LACTATION
Contra-indication: I trimester and the last 6 weeks of pregnancy; lactation period.
APPLICATION FOR FUNCTIONS OF THE LIVER
Contraindication: severe renal dysfunction.
APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS
Contraindications: marked violations of the liver.
APPLICATION FOR CHILDREN
In children, the drug is used only as directed by a doctor. Tablets are not used for children under 5 years.
SPECIAL INSTRUCTIONS
With caution and under the supervision of a doctor, the drug should be administered to patients with impaired liver and / or kidney function, with a tendency to hypotension, bronchospasm, and also with increased individual sensitivity to NSAIDs or non-narcotic analgesics.
With prolonged (more than a week) application, it is necessary to monitor the picture of peripheral blood and indicators of the functional state of the liver.
Sometimes metamizole metabolites can stain urine red.
OVERDOSE
In case of an overdose, the following symptoms may occur : vomiting, dry mouth, sweating, accommodation, hypotension, drowsiness, confusion, impaired liver and kidney function, convulsions.
Treatment is symptomatic.
DRUG INTERACTION
The simultaneous use of revalgine with other non-narcotic analgesics may lead to a mutual enhancement of toxic effects.
Tricyclic antidepressants, oral contraceptives, allopurinol disrupt metamizole metabolism in the liver and increase its toxicity.
Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the action of metamizole.
Simultaneous use with cyclosporine reduces the level of the latter in the blood.
Sedatives and tranquilizers increase the analgesic effect of Revalgine.
If you need to use these and other medications at the same time, you should consult your doctor.
TERMS OF RELEASE FROM PHARMACY
Without a doctor's prescription.
TERMS AND CONDITIONS OF STORAGE
Store in a dry place at a temperature of no higher than 25 В° C. Keep out of the reach of children. Shelf life - 3 years.
