Universal reference book for medicines
Product name: REAMBERIN ® (REAMBERIN ® )

Active substance: nonappropriate

Type: Preparation with detoxification action for parenteral use

Manufacturer: POLISAN NTFF (Russia) produced by RESTER (Russia)
Composition, form of production and packaging
Solution for infusions 1.5%
transparent, colorless.

1 l

meglumine sodium succinate * 15 g

* obtained according to the following formula: meglumine (N-methylglucamine) - 8.725 g, succinic acid - 5.28 g.

[PRING] sodium chloride - 6 g, potassium chloride - 0.3 g, magnesium chloride (in terms of anhydrous) - 0.12 g, sodium hydroxide - 1.788 g, water d / and - up to 1 liter.

Ionic composition per 1 liter: sodium ion-147.2 mmol, potassium ion-4 mmol, magnesium ion-109 mmol, succinate ion-44.7 mmol, N-methylglucammonium ion 44.7 mmol.

Osmolarity is 313 mOsm / kg.

100 ml - glass bottles (1) - packs of cardboard.

200 ml - glass bottles (1) - packs of cardboard.

400 ml - glass bottles (1) - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2010.

PHARMACHOLOGIC EFFECT

The drug with detoxication for parenteral use.
It has antihypoxic and antioxidant effect, having a positive effect on aerobic processes in the cell, reducing production of free radicals and restoring the energy potential of cells.
The drug activates the enzymatic processes of the Krebs cycle and promotes the utilization of fatty acids and glucose by cells, normalizes the acid-base balance and the gas composition of the blood.
Has a moderate diuretic effect.
PHARMACOKINETICS

With IV administration, the drug is quickly disposed of and does not accumulate in the body.

INDICATIONS

- as an antihypoxic and detoxification agent for acute endogenous and exogenous intoxications of various etiologies in adults and children older than 1 year.

DOSING MODE

Adults Reamberin ® are injected intravenously at a rate of no more than 90 cap / min (1-4.5 ml / min) in a volume of 400-800 ml / day.

The rate of drug administration and dosage is determined in accordance with the severity of the patient's disease.

For children over the age of 1 year Reamberin ® is administered intravenously at the rate of 6-10 ml / kg of body weight 1 time / day at a rate of 3-4 ml / min.
The daily dose of the drug should not exceed 400 ml.
The duration of the course of the drug should not exceed 11 days.

SIDE EFFECT

Perhaps: with the rapid administration of the drug, a brief feeling of heat, redness of the upper body.

CONTRAINDICATIONS

- a condition after a craniocerebral trauma, accompanied by an edema of the brain;

- severe renal dysfunction;

- Pregnancy;

- the period of lactation (breastfeeding);

- Hypersensitivity to the components of the drug.

With caution, the drug should be used for alkalosis.

PREGNANCY AND LACTATION

The drug is contraindicated for use in pregnancy and lactation.

APPLICATION FOR FUNCTIONS OF THE LIVER

Contraindicated in severe impairment of kidney function.

APPLICATION FOR CHILDREN

For children over the age of 1 year Reamberin ® is administered intravenously at the rate of 6-10 ml / kg of body weight 1 time / day at a rate of 3-4 ml / min.
The daily dose of the drug should not exceed 400 ml.
SPECIAL INSTRUCTIONS

Against the background of the use of Reamberin, an alkaline reaction of blood and urine is possible (due to the activation of aerobic processes in the body).

OVERDOSE

Data on the overdose of the drug Reamberin ® are not available.

DRUG INTERACTION

The drug can be used in combination with antibiotics, water-soluble vitamins and glucose solution.

TERMS OF RELEASE FROM PHARMACY

The drug is released by prescription.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children, protected from light at a temperature of 0 ° to 25 ° C;
a freeze is allowed. Shelf life - 5 years.
When the color of the solution changes or the presence of sediment, the use of the drug is unacceptable.

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