Universal reference book for medicines
Product name: HARTMAN'S SOLUTION

Active substance: compound solution of sodium lactate

Type: Preparation for rehydration and detoxification for parenteral use

Manufacturer: HEMOFARM (Serbia)
Description of the active substance:
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..
PHARMACHOLOGIC EFFECT
Means for rehydration. Provides reimbursement in the extracellular fluid of the three most important cations - Na + , K + , Ca 2+ . Lactate is metabolized in the body to bicarbonate, so the solution has an alkalizing effect.
After IV introduction, the solution passes into the tissues for no more than 30 minutes, so it can not be used instead of the indicated blood or plasma transfusion.
INDICATIONS
Hypovolemia and pronounced dehydration with normal KSHR or weak acidosis, incl. with the aim of compensating for water and electrolyte deficiencies due to severe vomiting and diarrhea, a large burn surface, with peritonitis, severe infection; to maintain the volume of extracellular fluid during and after surgery, which makes it possible to temporarily delay blood transfusion; for initial treatment with significant blood loss, shock, trauma.
DOSING MODE
In / in the dose up to 2500 ml / day, the average injection rate - 2.5 ml / kg or 60 drops / min, with urgent conditions - up to 100 drops / min. The amount of solution used depends on the clinical state of the patient.
SIDE EFFECT
When used in an inadequately high dose , a disturbance in the balance of water and electrolytes is possible, incl. Hypervolaemia, hypernatremia, hyperkalemia, hypercalcemia, hyperchloremia.
CONTRAINDICATIONS
Severe violations of liver function, acute renal failure, pulmonary edema, alkalosis, lactic acidosis, hypertonic dehydration.
PREGNANCY AND LACTATION
When pregnancy is used in cases where the expected benefit for the mother exceeds the possible risk to the fetus.
APPLICATION FOR FUNCTIONS OF THE LIVER
Contraindicated in acute renal failure.
With special care apply for violations of kidney function. In case of renal insufficiency, hemodialysis can be used with continuous monitoring of KShR.
APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS
Contraindicated in severe violations of liver function.
With extreme caution apply for liver diseases.
SPECIAL INSTRUCTIONS
It is used only for temporary maintenance of the volume of plasma in physiological limits, in urgent states. Do not use when severe deficiency of Na + , K + , Ca 2+ .
With extreme caution apply for chronic heart failure, renal dysfunction, liver disease and hypoproteinemia, as well as against corticosteroids and corticotropin treatment.
When applied in a large volume, it is necessary to control the KCHR.
In case of an overdose of the solution in most cases, it is sufficient to stop the administration. In case of renal insufficiency, hemodialysis can be used with continuous monitoring of KShR.
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