Universal reference book for medicines
Name of the preparation: PROPROTEN-100 (PROPROTEN-100)

Active substance: nonappropriate

ICD-10 codes (indications): F10.2, F10.3

Composition, form of production and packaging

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Drops for ingestion 100 g
25 ml - a bottle of a dropper of dark glass (1) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2010.

PHARMACHOLOGIC EFFECT

The preparation modifies the functional activity of the S-100 protein, which conjugates information and metabolic processes in the brain.
Sensitizes the neuronal membrane, modulates the synaptic plasticity of the neurons. Has a modifying effect on the functional state of brain structures involved in the formation of alcohol dependence: hypothalamus, hippocampus.
With alcohol dependence, it has a normalizing effect on the system of positive emotional reinforcement, which leads to a decrease in the frequency of self-stimulation of the lateral hypothalamus.
Reduces the bursting activity of neurons in the hippocampus; reduces the number of circulating immunocomplexes in the peripheral blood, which correlates with a decrease in ethanol consumption. Helps enhance the inhibitory effects of GABA in the central nervous system. It is experimentally established that the drug restores the neurotransmitter balance and conditioned reflex activity. Increases brain resistance to hypoxia and to toxic effects.
INDICATIONS

- Monotherapy of alcoholic withdrawal syndrome of mild and moderate severity.

It shows an anti-alcoholic effect, reduces the desire for alcohol and reduces the likelihood of relapses.

The drug facilitates both psychopathological disorders (anxiety, mental stress, insomnia, irritability, anxiety, mood reduction, intense craving for alcohol), and somatovegetative disorders (weakness, sweating, headache, tremor, tachycardia, digestive disorders) alcoholic hangover syndrome.

DOSING MODE

At 1 reception - 10 drops in a tablespoon of water (not during a meal).

In the state of a hangover in the first 2 hours, the drug is taken 10 drops every 30 minutes;
in the following 8-10 hours - 10 drops / 1 hour.
In case of sleep, the reception is resumed upon awakening.
Later on, when the condition improves, the drug is taken 10 drops every 2 to 3 hours (4-6 doses / day) for 2-3 days. When weighting the symptoms of alcohol withdrawal, it is necessary to attach medications traditionally used in detoxification.
For the prevention of recurrences, the drug is taken 10 drops 1-2 times / day for 2-3 months;
after accidental consumption of alcohol take an additional 10 drops of the drug 2 times (during the day and at night).
SIDE EFFECT

Possible reactions of individual hypersensitivity to the components of the drug.

OVERDOSE

To date, no cases of overdose have been observed.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

Store in a dark place at a temperature of no higher than 25 В° C.
Keep out of the reach of children. Shelf life - 2 years. Do not use after the expiration date.
The information is provided for your information, do not self-medicate, it is dangerous for your health.

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