Universal reference book for medicines
Product name: OXYMETAZOLINE (OXYMETAZOLINE)

Active substance: oxymetazoline

Type: Vasoconstrictive drug for topical application in ENT practice

Manufacturer: ФАРМСТАНСТАНАР-ЛЕКСРЕДСТВА (Russia)
Description of the active substance:
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..

PHARMACHOLOGIC EFFECT
Adrenomimetic agent for topical application.
Has vasoconstrictive effect. With intranasal administration, the swelling of the mucous membrane of the upper respiratory tract is reduced. When instilled into the conjunctival sac, it reduces the edema of the conjunctiva.
PHARMACOKINETICS
The effect manifests itself 15 minutes after application and lasts for 6-8 hours.

INDICATIONS
Difficulty of nasal breathing for colds, inflammation of the nasal sinuses, eustachyte, hay fever, allergic rhinitis, congestion and edema of the conjunctiva.

DOSING MODE
Apply locally.

SIDE EFFECT
On the part of the respiratory system: transient dryness and burning sensation of the nasal mucosa are possible, dry mouth and throat, sneezing;
with prolonged use, there may be reactive hyperemia of the mucosa, atrophy of the mucous membrane.
From the cardiovascular system: palpitation;
rarely - arterial hypertension.
From the side of the central nervous system: increased excitability, dizziness, headache, sleep disturbances;
with prolonged use - tachyphylaxis.
From the side of the digestive system: nausea.

From the side of the organ of vision: with conjunctival administration, it is possible to have mydriasis, paresis of accommodation, irritation of the conjunctiva and surrounding tissues, retraction of the eyelid.

CONTRAINDICATIONS
Inflammation of the nasal mucosa without secretion, chronic heart failure, hyperthyroidism, diabetes mellitus, pregnancy, children under 6 years (for eye drops), hypersensitivity to oxymetazoline, atrophic rhinitis, lactation period, arrhythmias, severe atherosclerosis, arterial hypertension, chronic renal failure , an angle-closure glaucoma.

PREGNANCY AND LACTATION
Oximetazoline is contraindicated in pregnancy and lactation (breastfeeding).

APPLICATION FOR FUNCTIONS OF THE LIVER
Contraindicated in chronic renal failure.

APPLICATION FOR CHILDREN
Contraindicated in children under 6 years (for eye drops).

SPECIAL INSTRUCTIONS
In the recommended dosage without consulting a doctor, you can use no more than 3 days.
Avoid getting the drug intended for intranasal administration in the eyes.
Impact on the ability to drive vehicles and manage mechanisms

The drug has an effect on vision, possibly reducing the reaction rate.

DRUG INTERACTION
With the simultaneous administration of MAO inhibitors and tricyclic antidepressants, an increase in blood pressure is possible.

Oxymetazoline slows the absorption of local anesthetic drugs, lengthens their action.

Co-administration of other vasoconstrictor drugs increases the risk of side effects.

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