Universal reference book for medicines
Product name: OXYCORT

Active substance: hydrocortisone, oxytetracycline

Type: The drug with antibacterial and anti-inflammatory action for external use

Manufacturer: TARCHOMIN PHARMACEUTICAL WORKS POLFA (Poland)
Composition, form of production and packaging
Aerosol for external use
in the form of a homogeneous suspension of yellow color, without mechanical inclusions, with a characteristic odor.

1 f.

Oxytetracycline hydrochloride 300 mg

hydrocortisone 100 mg

Excipients: sorbitan trioleate (Span 85V) - 640 mg, lecithin - 4.87 mg, isopropyl myristate - up to 5.25 g, a mixture of propane, butane and isobutane (Drivosol 35A) as a propellant - 27 g.

55 ml - aerosol bottles (1) with a valve and a spray device - packs cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2014.

PHARMACHOLOGIC EFFECT

Oxycort - a drug for external use, which has a combined effect of two active components.

Oxytetracycline is an antibiotic from the group of tetracyclines of a wide spectrum of action.
Has a bacteriostatic effect on certain gram-positive bacteria: streptococci;Gram-negative bacteria: rods Enterobacteriaceae, Pseudomonadaceae, Pasteurellaceae (Haemophillus spp.), cocci (Neisseria spp.). It is active against microorganisms of the family Rickettsiaceae, Chlamydiaceae, Mycoplasma, Actinomyces, and also some protozoa (Plasmodium, Entamoeba).
Hydrocortisone is a synthetic glucocorticosteroid of the adrenal cortex.
It has anti-inflammatory, anti-allergic, antipruritic and anti-edematous action.
PHARMACOKINETICS

Oxytetracycline in external application is practically not absorbed into the blood and does not have a systemic effect.
Hydrocortisone can penetrate insignificantly into the systemic bloodstream, undergoes metabolism in the liver, is excreted by the kidneys.
Violation of the integrity of the skin, inflammatory and other pathological processes of the skin, occlusive dressing contribute to the absorption of the drug.

INDICATIONS

- allergic skin diseases complicated by a secondary bacterial infection (hives, eczema);

- Skin diseases caused by microorganisms sensitive to oxytetracycline, as well as mixed infections (impetigo, furunculosis, folliculitis, multiple abscesses, erysipelas);

- burns and frostbites of the 1st degree;

- secondary infections after insect bites.

DOSING MODE

Outwardly.
Shake the bottle before use. Affected areas are sprayed with an aerosol spray for 3 seconds, keeping the bottle in a vertical position about 15-20 cm from the skin surface. The procedure is carried out 2-4 times / day at the same time intervals.
SIDE EFFECT

Local reactions: burning, itching, irritation in place of the application of the drug, dryness and atrophy of the skin, acne-like rash, secondary infections.
Prolonged use of the drug on the skin of the face can lead to the expansion of blood vessels, as well as to skin atrophy.
Possible development of systemic action: suppression of the hypothalamic-pituitary-adrenal system.
These effects can occur with prolonged use of the drug and applying it to a large surface of the skin.
CONTRAINDICATIONS

- hypersensitivity to the components of the drug;

- Tuberculosis of the skin;

- viral and fungal skin infections;

- tumors and neoplasms of the skin.

PREGNANCY AND LACTATION

The use of the drug during pregnancy and during lactation is contraindicated.

SPECIAL INSTRUCTIONS

In case of skin irritation, the drug should be canceled and appropriate measures initiated.

The use of oxytetracycline and other broad-spectrum antibiotics can lead to an increase in the number of resistant Staphylococcus strains and Candida albicans.
In case of development of infection caused by resistant strains of bacteria or yeast fungi, it is necessary to begin appropriate treatment.
The drug should not be applied to a large surface of the skin due to the possibility of the appearance of undesirable reactions characteristic of steroid preparations of systemic action, including oppression of the hypothalamic-pituitary-adrenal system (including symptoms of Cushing's syndrome, glucosuria).
In these cases, it is necessary to interrupt treatment and monitor the level of cortisol in the urine.
Long-term use of the drug on the skin can lead to the expansion of blood vessels and skin atrophy.

It is necessary to protect the eyes from the effects of aerosol.
Do not inhale the sprayed product. In case of contact with mucous membranes, rinse thoroughly with cool water.
The bottle must not be opened and heated.
the contents of the bottle are under pressure and easily ignited.
Impact on the ability to drive vehicles and manage mechanisms

The drug does not cause psychophysical disturbances, does not affect the ability to drive vehicles.

OVERDOSE

With topical application of the drug, symptoms of overdose were not observed.

DRUG INTERACTION

With topical application of the drug is not established.

TERMS OF RELEASE FROM PHARMACY

The drug is released by prescription.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children at a temperature of no higher than 25 °.
Shelf life - 2 years. Do not use after the expiration date printed on the package.
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