Universal reference book for medicines
Product name: SODIUM FLUORIDE (SODIUM FLUORIDE)

Active substance: sodium fluoride

Type: The drug for the prevention of caries for systemic use

Manufacturer: GRINDEX (Latvia)
Composition, form of production and packaging
Tablets for resorption for children
1 tab.

sodium fluoride 2.2 mg

10 pieces.
- blisters (3) - packs of cardboard.
250 pcs.
- Plastic bottles (1) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2014.

PHARMACHOLOGIC EFFECT

Sodium fluoride is an anti-caries prophylactic drug (especially in children and adolescents).
Fluorine ions directly affect the processes of mineralization of hard tooth tissues during their development. Additional introduction of fluorine provides the formation in the tissues of teeth the most stable form of apatite - fluorapatite. In addition, fluoride helps reduce cariogenic activity of plaque. It inhibits the formation of lactic acid from carbohydrates.
PHARMACOKINETICS

Absorption when ingested - 93-97%, TC max - 4 hours. At any dose, 50% of fluoride is stored in hard tissues of the tooth and bone tissue.
Accumulation in organs or soft tissues is not observed. It is excreted by the kidneys (not participating in the process of formation of bone tissue fluoride).
INDICATIONS

- prevention of tooth decay in children aged 2 to 14 years (if the concentration of fluoride in drinking water does not exceed 0.7 mg / l).

DOSING MODE

Children aged 2 to 6 years - 1 tablet (1.1 mg) 1 time per day.
Children over 6 years - 1 tablet (2.2 mg) or 2 tablets (1.1 mg) 1 time per day.
It is recommended to take the drug before going to bed after brushing your teeth.
The tablet is kept in the mouth until it is completely resorbed. Duration of treatment is at least 250 days per year, annually up to 15 years of age.
It is not recommended to simultaneously use medicines containing calcium.

SIDE EFFECT

Nausea, vomiting, decreased appetite, fatigue, headache, diarrhea, ossification of the attachment sites of tendons and ligaments, hypothyroidism (with prolonged use), allergic reactions, rhinitis, zosinophilia, skin rash, fluorosis (violation of the formation and calcification of the enamel, the appearance of yellow , brown spots, finesse, increased fragility and abrasion of the teeth).

CONTRAINDICATIONS

hypersensitivity;

- hypothyroidism;

- Stomach ulcer and duodenal ulcer (in the stage of exacerbation);

- Hepatic and / or renal insufficiency;

- Pregnancy;

- lactation period;

- Children under 2 years;

- Living in an area with a sufficient content of fluoride in water (above 0.7 mg / ml).

Sodium fluoride tablets for resorption for children, orange 1.1 mg contain aspartame - a source of phenylalanine.
This drug should not be taken in patients with phenylketonuria.
Sodium fluoride tablets for resorption for children 2.2 mg contain lactose.
This drug should not be taken to patients with a rare congenital galactose intolerance, lactase deficiency or malabsorption of glucose-galactose.
PREGNANCY AND LACTATION

Contraindicated in pregnancy and lactation


APPLICATION FOR FUNCTIONS OF THE LIVER

Contraindicated in renal insufficiency


APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

Contraindicated in liver failure.

APPLICATION FOR CHILDREN

The drug is used in children aged 2 to 14 years.
Contraindicated for children under 2 years.
SPECIAL INSTRUCTIONS

Do not exceed recommended doses and follow the directions of the dentist.

Ensure that the child does not receive fluoride additionally while taking other drugs or nutritional supplements at the same time.

Use in children under 6 years of age requires special control.

In order to avoid the development of fluorosis it is desirable to regularly perform a dental examination of the teeth in a child at least 1-2 times a year.

OVERDOSE

Symptoms: lacrimation, hypersalivation, nausea, decreased appetite, vomiting, diarrhea, abdominal pain, pain in the lower extremities, arthralgia, fatigue, miosis, impaired vision, weakness, myasthenia gravis, tremor, convulsions, fever, tachycardia, pressure, respiratory failure, respiratory arrest.

Treatment: the administration of large amounts of liquid and calcium (a solution of calcium gluconate or calcium lactate, milk) to precipitate fluorides;
gastric lavage with acidified water or 1% solution of sodium chloride, the appointment of salt laxatives, iv administration of electrolytes (20 ml of 10-20% calcium gluconate solution), vitamins; symptomatic therapy, control of calcium concentration in the blood; hemodialysis.
DRUG INTERACTION

Sodium fluoride absorption reduces antacids (prematurely dissolve the shell);
Antacids should be used no earlier than 2 hours before taking sodium fluoride.
Vitamins A and D contribute to the development of ectopic calcification.

TERMS OF RELEASE FROM PHARMACY

On prescription.

TERMS AND CONDITIONS OF STORAGE

Store at a temperature not exceeding 25 ° C.
Keep out of the reach of children! Shelf life - 5 years.
Alphabetical index of medicines:
A  B  V  G  D  E  J
Z  I  Y  K  L  M  N
O  P  R  S  T  U  F
H  C  CH  SH  E  U  Y
Rambler's Top100
Privacy policy:
Copyright 2009 - 2017. Universal reference book of medicines. All rights reserved.
When using site materials, an active hyperlink is required!