Universal reference book for medicines
Product name: MATAREN ® PLUS (MATAREN PLUS)

Active substance: Capsicum, meloxicam

Type: The drug with anti-inflammatory, analgesic and local irritant effect

Manufacturer: NIZHFARM (Russia)
Composition, form of production and packaging
Cream for external use
from light yellow to dark yellow color;
a reddish-brown tinge is allowed.
1 g

meloxicam 30 mg

tincture of peppercorn fruits 100 mg

Auxiliary substances: chloroform 25 mg, coriander oil 2.5 mg, lavender oil 2.5 mg, liquid paraffin (Vaseline oil medical) 50 mg, propylene glycol 25 mg, stearic acid (stearic acid) acid 50) - up to 20 mg, distilled monoglycerides (Dimodan HP) - up to 20 mg, emulsion wax 7.5 mg, glycerol (glycerin distilled) 25 mg, poloxamer (emixol 268) 5 mg, carbomer (carbopol) 3 mg , sodium hydroxide - 0.6 mg, imidourea (Germall ® ) - 3 mg, water (purified water) - up to 1 g.

20 g - aluminum tubes (1) - packs of cardboard.

30 g - aluminum tubes (1) - cardboard packs.

40 g - aluminum tubes (1) - packs of cardboard.

50 g - aluminum tubes (1) - packs of cardboard.

100 g - aluminum tubes (1) - packs of cardboard.

20 g - polyethylene tubes (1) - packs of cardboard.

30 g - polyethylene tubes (1) - cardboard packs.

40 g - polyethylene tubes (1) - cardboard packs.

50 g - polyethylene tubes (1) - cardboard packs.

100 g - polyethylene tubes (1) - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2012.

PHARMACHOLOGIC EFFECT

Matarin Plus has an anti-inflammatory, analgesic, anti-edematous effect, can cause mild local flushing of the skin without causing a pronounced irritant effect on the skin.

Matarin Plus also reduces pain in the joints (including in the joints of the spine) and in muscles at rest and during movement, contributes to an increase in the volume of motion of the joints (in the area of ​​application of the cream).
Reduces morning stiffness and swelling of the joints.
Meloksikam selectively inhibits cyclooxygenase 2, disrupts the metabolism of arachidonic acid, reduces the number of prostaglandins (mediators of pain and inflammation) in the inflammatory focus.

Tincture of chilli pepper contains capsaicin, which has irritating effect on sensitive skin receptors, which leads to local analgesic effect, to improvement of blood circulation in the skin and subcutaneous tissue, and also to the warming effect.
Improvement of local blood flow is accompanied by increased blood circulation in the underlying tissues, which helps to remove the inflammation substrate from the pathological focus.
Due to the optimal combination of the components of the cream, the mutual enhancement of their analgesic and anti-inflammatory effects is noted.
When combined, the active components of the Matarin ® Plus cream have a greater effect due to synergy, compared to the individual effect of each of these components.
INDICATIONS

- inflammatory and degenerative diseases of the musculoskeletal system;

- rheumatic affections of soft tissues;

- pain syndrome: bursitis, tendonitis, lumbago, sciatica, neuralgia, myalgia, arthralgia, radiculitis, posttraumatic pain syndrome (traumatic bruises, sprains, sprains, muscles and tendons, muscle ruptures without compromising the integrity of the skin), tenderness of muscles and joints, caused by heavy physical exertion.

DOSING MODE

Outwardly.
Slightly rub strip of cream length from 1 to 5 cm, the frequency of application - 1-3 times / day. The amount of cream and frequency of application can vary depending on the area of ​​application and individual reaction to the cream. To enhance the effect, a dry warming bandage can be applied.
SIDE EFFECT

The resulting side effects depend on individual sensitivity.

There may be allergic reactions from the skin (itching, skin rash), skin peeling, hyperemia.

If any side effects occur, the patient should stop using the cream and consult a doctor.

CONTRAINDICATIONS

- children's age till 12 years;

- violations of the integrity of the skin and inflammatory skin diseases at the site of the intended application of the drug;

- Hypersensitivity to the components of the drug.

With caution should prescribe the drug in violation of kidney and liver, a pronounced pathology of the gastrointestinal tract (peptic ulcer of the stomach and duodenal ulcer in the phase of exacerbation), severe pathology of the blood system, in childhood from 12 to 18 years.

PREGNANCY AND LACTATION

The use of the drug is contraindicated in pregnancy and lactation.

APPLICATION FOR FUNCTIONS OF THE LIVER

Caution should be given to the drug in case of impaired renal function.

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

With caution should prescribe the drug in violation of liver function.

APPLICATION FOR CHILDREN

Contraindicated in children under 12 years.

With caution should prescribe the drug in adolescence from 12 to 18 years.

SPECIAL INSTRUCTIONS

Avoid getting the product on the damaged surface of the skin, eyes and mucous membranes.
If you get Matarin ® Plus cream on these areas, you should remove it with a cotton swab impregnated with petroleum or vegetable oil.
After using the drug, you should thoroughly wash your hands.

The patient should consult a physician before sharing the cream of Mataren ® Plus with other NSAIDs, and also if the drug is needed for more than 10 days.

OVERDOSE

Cases of overdose of Mataren ® Plus are unknown.

DRUG INTERACTION

At present, there is no data on the interaction of Mataren Plus with other drugs.

TERMS OF RELEASE FROM PHARMACY

The drug is released by prescription.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children at a temperature of no higher than 25 ° C.
Shelf life - 2 years.
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