Universal reference book for medicines
The name of the preparation is: MARENA DYE EXTRACT (RUBIAE TINCTORUM EXTRACT)

Active substance: Rubia tinctorum

Type: Phytopreparation with diuretic, spasmolytic and litholytic action

Manufacturer: ФАРМЦЕНТР ВИЛАР (Russia)
Composition, form of production and packaging
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Tablets from light brown to brown, with darker or lighter blotches, biconvex, with a risk.
1 tab.

dry extract of rhizomes with roots of madder dyeing 250 mg

Excipients: lactose (sugar milk), potato starch, silicon dioxide colloid (aerosil A-380), calcium stearate, croscarmellose sodium.

10 pieces.
- packings of cellular contour (1) - packs cardboard.
10 pieces.
- packings cellular planimetric (2) - packs cardboard.
10 pieces.
- packings cellular planimetric (3) - packs cardboard.
20 pcs.
- packings of cellular contour (1) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2010.

PHARMACHOLOGIC EFFECT

Spasmolytic agent of plant origin.
The main active substance of the drug is the madder's dye extract, obtained from the rhizomes and roots of the madder dye, Rubia tinctorum L. and its Georgian variety Rubia tinctorum L. var.iberica Fisch. Ex DC. (R.iberica Fisch. Ex DC.) Koch sem. madder - Rubiaceae.
The extract of madder dry dye has a diuretic and spasmolytic effect, promotes loosening of urinary calculi containing calcium and magnesium phosphates and their removal from the kidneys and urinary tract.

PHARMACOKINETICS

In accordance with the International Convention (EMEAHMPWG11 / 99), clinical studies of herbal preparations do not require an isolated study of pharmacokinetic parameters.

INDICATIONS

- urolithiasis in adults - to reduce spasms and facilitate the removal of small stones and sand.

DOSING MODE

The drug is administered orally 1 tablet.
3 times / day. If necessary, the dose can be increased to 2-3 tablets. 3 times / day. Tablets before taking should be dissolved in 1/2 cup of warm water.
The course of treatment is 20-30 days.
Conducting a second course of treatment is possible in 4-6 weeks after consulting a doctor.
SIDE EFFECT

Possible: allergic reactions.

When using madder preparations, the dye is dyed reddish;
when the urine is sharply stained to brownish-red, it is necessary to reduce the dose or temporarily interrupt the course of treatment.
CONTRAINDICATIONS

- acute and chronic glomerulonephritis;

- severe renal failure;

- stomach ulcer;

- Galactose intolerance, lactase deficiency or malabsorption of glucose-galactose;

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

Data on the safety of the drug Marena dye extract is not provided.

APPLICATION FOR FUNCTIONS OF THE LIVER

Contraindicated use of the drug in acute and chronic glomerulonephritis, with severe renal failure.

OVERDOSE

Overdose of madder preparations dyeing can cause pain associated with the removal of stones.

DRUG INTERACTION

Data on the interaction of the drug Marena dye extract are not provided.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children, dry place at a temperature of no higher than 15 ° C.
Shelf life - 2 years.
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