Universal reference book for medicines
Product name: MAXIDEX (MAXIDEX)

Active substance: dexamethasone

Type: GCS for topical application in ophthalmology

Manufacturer: sa ALCON-COUVREUR nv (Belgium)
Composition, form of production and packaging
Suspension-eye drops 0.1%
1 ml

dexamethasone 1 mg

Excipients: benzalkonium chloride, hydroxypropylmethylcellulose, purified water.

5 ml - a bottle of dropper plastic "Drop-Teiner" (1) - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2005.

PHARMACHOLOGIC EFFECT

GCS for topical application in ophthalmology.
Has a pronounced anti-inflammatory, antiallergic and desensitizing effect. Dexamethasone actively suppresses inflammatory processes, inhibiting the eosinophilic ejection of inflammatory mediators, the migration of mast cells and decreasing the permeability of capillaries.
The drug does not have mineralocorticoid activity.

PHARMACOKINETICS

Data on the pharmacokinetics of the Maxidex preparation are not available.

INDICATIONS

- allergic blepharitis;

- allergic conjunctivitis;

- allergic keratoconjunctivitis;

- acute and chronic iritis;

- Iridocyclitis;

- prevention and treatment of inflammatory reactions in the postoperative period;

- thermal and chemical burn (after complete epithelialization of corneal defects).

DOSING MODE

The drug is instilled in 1-2 drops in the conjunctival sac of the affected eye (or eyes) every 3-6 hours.

SIDE EFFECT

From the side of the organ of vision: with long-term topical application of GCS may be noted: increased intraocular pressure with possible subsequent development of glaucoma;
formation of posterior subcapsular cataract; slowing down the process of wound healing (with diseases that cause thinning of the cornea or sclera, possibly perforation of the fibrous membrane).
After the application of preparations containing GCS, the development of a secondary infection (including fungal infection) can be observed, as a result of the suppression of the protective reaction of the patient's body.
In acute purulent diseases, the eyes of the SCS can mask or strengthen the existing infectious process. The appearance of non-healing ulcers on the cornea after prolonged treatment with steroid preparations may indicate the development of fungal infestation.
CONTRAINDICATIONS

- viral, bacterial and fungal infections of the eyes;

- corneal diseases in combination with epithelial defects;

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

In pregnancy, Maxidex should be given only in cases where the expected therapeutic effect exceeds the potential risk to the fetus or child.

If it is necessary to prescribe the drug during lactation, breastfeeding should be interrupted.

APPLICATION FOR CHILDREN

At present, safety and efficacy of the drug in children have not been established.

SPECIAL INSTRUCTIONS

When using preparations containing GCS, the intraocular pressure should be measured regularly for more than 10 days.

The drug is intended for topical use only (not for injection).

During treatment it is not recommended to wear contact lenses.

Avoid touching the tip of the dropper to any surfaces to avoid microbial contamination of the contents of the vial.

Before use, shake the contents of the vial.

Use in Pediatrics

At present, safety and efficacy of the drug in children have not been established.

OVERDOSE

Currently, there have been no reports of overdoses of Maxixx.

DRUG INTERACTION

Clinically significant drug interaction of the drug Maxiex with other drugs is not established.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of the reach of children at a temperature of 8 ° to 30 ° C.
Shelf life - 3 years. After opening the vial, the drug should be used within 4 weeks.
Conditions of leave from pharmacies

The drug is released by prescription.

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