Universal reference book for medicines
Product name: MAXAR (MAKSAR)

Active substance: nonappropriate

Type: Hepatoprotector of plant origin

Producer: Pacific Institute of Bioorganic Chemistry, Far East Division, Russian Academy of Sciences (Russia)
Composition, form of production and packaging
The tablets covered with a film membrane of
yellow color, biconvex.

1 tab.

Extract of wood of Maacia Amur 60 mg

with the content of the sum of stilbenes and isoflavones not less than 19.8%

Excipients: dextrose monohydrate 16.43 mg, potato starch 63.97 mg, magnesium stearate 2.08 mg, microcrystalline cellulose 65.52 mg.

Composition of the film membrane: hypromellose 6.5 mg, tropeolin-O 20 μg, silicon dioxide colloid 650 μg, talc 1.3 mg, titanium dioxide 1.53 mg.

50 pcs.
- cans (1) - packs cardboard.
100 pieces.
- cans (1) - packs cardboard.
10 pieces.
- blisters (1) - packs of cardboard.
10 pieces.
- blisters (2) - packs of cardboard.
10 pieces.
- blisters (3) - packs of cardboard.
10 pieces.
- blisters (4) - packs of cardboard.
10 pieces.
- blisters (5) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2011.

PHARMACHOLOGIC EFFECT

The therapeutic effect of Maksar ® is due to the complex of biologically active substances of dry extract made from the maakia of Amur wood, the most important of which are isoflavones (formononetin, genistein, retuzin, maakiasin) and stilbenes (resveratrol and piceatanol).

Maxar ® has a hepatoprotective, choleretic effect, it helps to normalize the impaired histoarchitectonics of the liver, while the number of necrotic hepatocytes decreases, the protein and fatty degeneration of the liver parenchyma is eliminated.
Maxar ® inhibits the reactions of lipid peroxidation; improves the respiratory function of mitochondria; stabilizes the membrane with lysosomes and inhibits the release of necrosogenic hydrolases, including phospholipase A; stimulates the processes of oxidation and conjugation of xenobiotics, glucuronidation of bilirubin; increases the excretory function of the liver; reduces hyperfermentation (aminotransferase, lactate dehydrogenase, alkaline phosphatase). With chronic hepatitis, the drug, suppressing the lipid peroxidation-stimulated synthesis of collagen and glucosaminoglycans, inhibits the formation of fibrosis inside the hepatic lobules, providing anti- necrotic and anti-inflammatory effects.
Maksar ® has a choleretic effect: increases the rate of bile secretion and excretion of fatty acids, bilirubin and cholesterol into it.

INDICATIONS

In adults, in the treatment of acute and chronic hepatitis, liver cirrhosis, fatty hepatosis;
in the syndrome of cholestasis.
DOSING MODE

Inside 1 tablet 3 times a day for 30-40 minutes before meals.
Duration of treatment - 4 weeks. An increase in the duration and conduct of repeated courses of treatment is possible on the recommendation of a doctor.
SIDE EFFECT

Allergic reactions are possible.

CONTRAINDICATIONS

Hypersensitivity to the components of the drug;
pregnancy, lactation, age under 18, cholelithiasis (exacerbation period).
PREGNANCY AND LACTATION

Contraindicated during pregnancy, during lactation.

APPLICATION FOR CHILDREN

Contraindicated at the age of 18 years.

SPECIAL INSTRUCTIONS

The drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

TERMS OF RELEASE FROM PHARMACY

The drug is released by prescription.

TERMS AND CONDITIONS OF STORAGE

The drug is stored in a dry, dark place at a temperature of 8 to 25 ° C.
Keep out of the reach of children.
Shelf life - 3 years.
Do not use the drug after the expiration date.
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