Universal reference book for medicines
Product name: LEVOMYCETIN (LEVOMYCETIN)

Active substance: chloramphenicol

Type: Antibiotic for topical application in ophthalmology

Producer: Pharmaceutical firm LEKKO (Russia)
Composition, form of production and packaging
Eye drops 0.25%
1 ml

chloramphenicol 2.5 mg

5 ml - a bottle-droppers polymer (1) - packs cardboard.

10 ml - a bottle-droppers polymer (1) - packs cardboard.

INSTRUCTION FOR THE SPECIALIST.

The product description was approved by the manufacturer for the 2009 print edition.

PHARMACHOLOGIC EFFECT

Levomycetin is a broad-spectrum antibiotic;
is effective against many gram-positive cocci (gonococci and meningococci), various bacteria (intestinal and hemophilic rods, salmonella, shigella, klebsiella, serratsii, iersbnia, proteus), rickettsia, spirochaete and some large viruses. The drug is active against strains resistant to penicillin, streptomycin, sulfonamides. It is weakly active against acid-fast bacteria, Pseudomonas aeruginosa, clostridia and protozoa.
It acts bacteriostatically.
The mechanism of antibacterial action is associated with a violation of the synthesis of proteins of microorganisms.
Drug resistance to the drug develops relatively slowly, with, as a rule, no cross-resistance to other chemotherapeutic agents.

PHARMACOKINETICS

The therapeutic concentration of levomycetin in topical application is created in the cornea, watery moisture, iris, vitreous;
the drug does not penetrate into the lens.
It is excreted mainly with urine in the form of inactive metabolites.

INDICATIONS

Prevention and treatment of eye infections:

- Conjunctivitis;

- blepharitis;

- keratitis.

DOSING MODE

The drug is instilled in the conjunctival sac by 1 drop 3-4 times / day.

If the patient takes the drug at his discretion, then it is not recommended to use more than three days without consulting a doctor.

SIDE EFFECT

Perhaps the development of allergic reactions.

CONTRAINDICATIONS

- oppression of hematopoiesis;

- Skin diseases (psoriasis, eczema, fungal diseases);

- Pregnancy;

- newborn children;

- Individual intolerance to the drug.

PREGNANCY AND LACTATION

Contraindicated in pregnancy.

APPLICATION FOR CHILDREN

Contraindicated in newborns.

DRUG INTERACTION

To prevent an increase in the oppressive effect on the blood, joint use with sulfanilamide preparations is not recommended.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

List B. Store in a place protected from light, out of the reach of children, at a temperature of no higher than 30 ° С.
Shelf life - 2 years. After opening the vial, use the solution for 30 days.
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