Universal reference book for medicines

Active substance: nonappropriate

Type: A drug regulating the balance of the intestinal microflora (probiotic)

Producer: NGO MIKROGEN (Russia)
Composition, form of production and packaging
? Tablets 1 tab.
Lactobacillus acidophilus 2 billion CFU
20 pcs. - bottles (5) - packs of cardboard.
20 pcs. - bottles (10) - packs of cardboard.
? Tablets 1 tab.
Lactobacillus acidophilus 4000000000 cfu
3 doses - bottles (10) - packs of cardboard.
5 doses - bottles (10) - packs of cardboard.
Description of the drug approved by the manufacturer for the printed edition of 2013.
The therapeutic effect of the drug is due to the antagonistic effect of lactobacilli in relation to pathogenic and opportunistic microorganisms, including staphylococci, enteropathogenic E. coli, protea, shigella, which determines the corrective action of the drug in cases of bacteriocenosis. The drug improves metabolic processes, prevents the formation of protracted forms of intestinal diseases, increases the nonspecific resistance of the body.
In diseases of the gastrointestinal tract:
- reconvalescents that have transferred acute intestinal infections, in the presence of bowel dysfunctions or the isolation of pathogenic and conditionally pathogenic bacteria;
- Somatic diseases complicated by dysbiosis caused by the use of antibiotics, chemotherapy and other causes;
- complex treatment of weakened children with diseases of infectious and non-infectious etiology, accompanied by dysbiosis and atopic dermatitis;
- Chronic colitis of various etiologies, including ulcerative colitis.
In diseases of the female sexual sphere:
- for sanation of the genital tract with nonspecific inflammatory diseases of the genitals and prenatal preparation of the pregnant "risk" group with impaired purity of the vaginal secretion to grade III-IV.
Lactobacterin for intestinal diseases is used inside, and in obstetric-gynecological practice - intravaginally.
The contents of the vial should be diluted with boiled water at room temperature at a rate of 5 ml (a teaspoon) of water per 1 dose of the drug.
Dissolve as follows: pour the required amount of water in a glass (according to the number of doses indicated on the vial); open the bottle by removing the cap and stopper; from the glass to transfer a small amount of water into the bottle; after dissolving (the preparation dissolves no more than 5 minutes with the formation of a homogeneous suspension of whitish-gray or yellowish-beige color), transfer the contents of the vial into the same beaker and mix. One teaspoon of the drug dissolved in this way is 1 dose.
For intestinal diseases, the drug should be taken 40-60 minutes before meals and preferably washed down with milk. Treatment is recommended to accompany the use of vitamins.
At intestinal diseases lactobacterin is used in the following daily doses:
Age Dose
Up to 6 months 3 doses 2 times a day
From 6 months to 1 year 3 doses 3 times a day
From 1 to 3 years 5 doses 2 times a day
Older than 3 years and adults 5 doses 2-3 times a day
The course of treatment with lactobacterin for various diseases is:
a) in case of prolonged and chronic course of dysentery, postdisenteric colitis, after treatment of convalescents after acute intestinal infection, as well as with prolonged intestinal dysfunction of unknown etiology, treatment - at least 4-6 weeks;
b) with nonspecific ulcerative colitis, as well as chronic colitis and enterocolitis - up to 2 months;
c) with dysbacteriosis of different etiology - 3-4 weeks.
In the absence of effect from the use of the drug for 2 weeks, it is necessary to re-examine the microflora of the gastrointestinal tract and correct it with other drugs, depending on the result obtained.
To fix the obtained clinical effect or in the absence of complete normalization of microflora after the end of the course of treatment, in diseases that occur with relapses, repeated courses of treatment are advisable. In these cases, prior to the appointment of the drug, a re-examination of the microflora is necessary. Supportive doses of the drug (half the daily dose) are prescribed after 2-3 weeks for 1-1.5 months.
In inflammatory diseases of the genitalia, lactobacterin is prescribed 5 doses 2 times a day intravaginally for 10-12 days, starting from 10-12 days of the menstrual cycle. For prenatal preparation of pregnant women of the "risk" group, lactobacterin is prescribed for 5 doses 1 time per day for 5-8 days.
For intravaginal application, the contents of the vial should be dissolved in 5-10 ml of boiled water at room temperature, impregnated with a sterile swab with a dissolved preparation, inserted into the vagina and left for 2-3 hours.
Treatment is carried out under the control of restoration of purity of the vaginal secretion to I-II degree, the appearance of lactoflora and the disappearance of clinical symptoms of the disease.
There was no reaction to the administration of the drug.
vulvovaginal candidiasis.
Precautions for use.
Dissolved drug is not subject to storage. A drug whose package integrity is broken (cracked bottles), a drug without labeling, a drug with altered physical properties (discoloration, shrinkage of biomass), with foreign impurities, is unsuitable for use.
Impact on the ability to drive vehicles and manage mechanisms
Not registered.
Due to the high antibiotic resistance of lactobacilli, the use of lactobacterin dry with antibiotic therapy is allowed.
Without recipe.
In accordance with SP at a temperature not exceeding 10 ° С. Keep out of the reach of children. Shelf life of the drug is 1 year (at a dose of at least 2x10 9 live lactobacilli); 2 years (with a content of at least 4x10 9 live lactobacilli in one dose).
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