Universal reference book for medicines
Product name: LAXYGAL (LAXYGAL)

Active substance: sodium picosulfate

Type: Laxative drug that stimulates intestinal motility

Manufacturer: Teva Pharmaceutical Industries (Israel) manufactured by TEVA Czech Industries (Czech Republic)
Composition, form of production and packaging
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Drops for ingestion as a clear liquid from colorless to slightly yellow-brown in color.
1 ml of 1 fl.

sodium picosulphate 7.5 mg 75 mg

Excipients: sorbitol solution 70% (non-crystallisable), ethylparahydroxybenzoate sodium, hydrochloric acid 35%, purified water.

10 ml - a bottle of a dropper of dark glass (1) - packs cardboard.

25 ml - a bottle of a dropper of dark glass (1) - packs cardboard.

INSTRUCTION FOR THE SPECIALIST.

The product description was approved by the manufacturer for the 2009 print edition.

PHARMACHOLOGIC EFFECT

Laxative.
The active form of the preparation, formed by hydrolysis under the influence of intestinal microorganisms, directly excites the nerve structures of the intestinal wall, as a result of which the movement of intestinal contents accelerates, the absorption of electrolytes and water decreases.
The action occurs 10-12 hours after admission.

PHARMACOKINETICS

After oral administration, it is not absorbed from the digestive tract and does not undergo hepatic intestinal circulation.

INDICATIONS

- Atonic constipation;

- regulation of the stool (hemorrhoids, proctitis, anus fractures);

- preparation for surgical operations, instrumental and roentgenological studies.

DOSING MODE

Inside in a small amount of water, before going to bed.

Adults and children over 10 years - 12-24 drops.
Children aged 4 to 10 years - 6-12 drops.
Depending on the effect obtained, the dose in subsequent administration is increased or decreased.

SIDE EFFECT

Possible: diarrhea, abdominal pain, dehydration, water-electrolyte balance disorders, weakness, convulsions, decreased blood pressure.

CONTRAINDICATIONS

- intestinal obstruction;

- strangulated hernia;

- acute inflammatory diseases of the abdominal cavity;

- peritonitis;

- Abdominal pain (of unknown origin);

bleeding from the gastrointestinal tract;

- Metrorrhagia;

- Cystitis;

- severe dehydration;

- Spastic constipation;

- Children's age (up to 4 years);

- Pregnancy (I trimester);

hypersensitivity.

With care - the period of lactation.

PREGNANCY AND LACTATION

When pregnancy should be used only as directed by a doctor.
Contraindication: pregnancy (I trimester).
With care - the period of lactation.

APPLICATION FOR CHILDREN

Contraindication: children's age (up to 4 years).
At the age of 4 to 10 years, a corrective dose is required (see Dosage regimen).
SPECIAL INSTRUCTIONS

Not
should be used daily without medical supervision for more than 10 days.
Children should only be used for the appointment of a doctor.

OVERDOSE

Symptoms: see the "Side effect" section.
In addition, with a chronic overdose it is possible to develop ischemia of the mucous membrane of the colon, secondary hyperaldosteronism, urolithiasis, and damage to the renal tubules.
Treatment: gastric lavage, correction of water-electrolyte balance disorders, antispasmodics.

DRUG INTERACTION

Perhaps increased sensitivity to cardiac glycosides.

GCS, diuretics increase the risk of electrolyte disturbances.

Antibiotics of a wide spectrum of action reduce a laxative effect.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

Store at a temperature of 10 ° C to 25 ° C, protected from
light and inaccessible place for children. Shelf life - 3 years.
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