Universal reference book for medicines
Name of the drug: Kurizoin В® (CURIOSIN)

Active substance: zinc hyaluronate

Type: Preparation, improving trophic and tissue regeneration, with antimicrobial activity for external use

Manufacturer: GEDEON RICHTER-RUS (Russia), manufactured by GEDEON RICHTER (Hungary), commissioned by GEDEON RICHTER-RUS (Russia)
Composition, form of production and packaging
The solution for external use is
colorless or slightly colored, transparent, viscous.

1 ml of 1 fl.

zinc hyaluronate * 2.05 mg 20.5 mg

* Produced by prescription: sodium hyaluronate - 20 mg, zinc chloride - 10.5 mg

Excipients: potassium sorbate - 10 mg, sorbitol - 464 mg, water d / and - up to 10 ml.

10 ml - a bottle-droppers polyethylene (1) - packs cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2011.

PHARMACHOLOGIC EFFECT

Stimulator of tissue repair.
When the hyaluronic acid interacts with water molecules, a dispersion matrix arises, replenishing the missing cellular tissue. It forms a natural supporting framework for cells involved in wound healing, increases the activity of granulocytes and macrophages, enhances fibroblast proliferation and angiogenesis. Compared with sodium hyaluronate, zinc hyaluronate has a bacteriostatic effect against many bacteria.
PHARMACOKINETICS

When topical application is practically not absorbed, a small amount of the drug is detected in the plasma.

INDICATIONS

- as part of complex therapy for local treatment of poorly healing, infected wounds, shin ulcers, bedsores, fistulas, and also to accelerate the normal healing of wounds.

DOSING MODE

Outwardly.
The solution is applied 1 time / day to the damaged skin in a maximum dose of 1 drop / cm 2 .
After preliminary washing of the wound surface with physiological solution or if necessary with a 3% solution of hydrogen peroxide, several drops of KuriosinВ® solution should be applied to the gauze pad in an amount necessary to uniformly moisten the entire wound surface at a maximum dose of 1 drop / cm 2 .
Cover the wound with a sterile gauze napkin or bandage that does not stick to the wound surface. On the strongly wetting wounds the solution can be applied 2 times / sut. The duration of therapy is individual and depends on the form and severity of the disease.
SIDE EFFECT

At the beginning of treatment, there may be a slight burning sensation, which gradually disappears.

Very rarely in the adjoining areas of the skin, allergic reactions (irritation and contact dermatitis) are possible.

CONTRAINDICATIONS

- Pregnancy;

- the period of breastfeeding;

- Hypersensitivity to any of the components of the drug.

PREGNANCY AND LACTATION

There is no data on the use of the drug during pregnancy and during breastfeeding.

APPLICATION FOR FUNCTIONS OF THE LIVER

Data on the use of the drug in patients with impaired renal function are not provided.

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

Data on the use of the drug in patients with impaired liver function are not provided.

APPLICATION FOR CHILDREN

Information about the prescription of the drug to children is not provided.

APPLICATION IN ELDERLY PATIENTS

Data on the use of the drug elderly patients are not provided.

SPECIAL INSTRUCTIONS

Does not cause photosensitivity, does not stain skin and linen.

OVERDOSE

Not described.

DRUG INTERACTION

Data on interactions with other drugs have not been provided.

TERMS OF RELEASE FROM PHARMACY

The drug is released by prescription.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children at a temperature of 15 В° to 30 В° C.
Shelf life - 2 years. Do not use after the expiry date printed on the package.
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