Composition, form of production and packaging
? Spray nasal 0.05% in the form of a transparent, colorless to slightly colored liquid.
1 ml
xylometazoline hydrochloride 500 Ојg
Excipients: sodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate dihydrate, disodium edetate, sodium chloride, purified water.
10 ml - plastic bottles with a dispenser (1) - packs cardboard.
? Spray nasal 0.1% in the form of a transparent, colorless to slightly colored liquid.
1 ml
xylometazoline hydrochloride 1 mg
Excipients: sodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate dihydrate, disodium edetate, sodium chloride, purified water.
10 ml - plastic bottles with a dispenser (1) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2011.
PHARMACHOLOGIC EFFECT
Xylometazoline belongs to the group of local vasoconstrictors (decongestants) with alpha-adrenomimetic action, causes narrowing of the blood vessels of the nasal mucosa, thus eliminating the edema and hyperemia of the nasopharyngeal mucosa. Relieves nasal breathing in rhinitis.
Ximelin Eco does not contain preservatives. In therapeutic concentrations, it does not irritate the mucous membrane, it does not cause hyperemia. The action comes in a few minutes and lasts for 10-12 hours.
PHARMACOKINETICS
With topical application is practically not absorbed, plasma concentrations are so small that they can not be determined by modern analytical methods.
INDICATIONS
- acute respiratory diseases with phenomena of rhinitis (common cold);
acute allergic rhinitis;
- Pollinosis;
- sinusitis;
- Eustachyte;
- otitis media (to reduce edema of the nasopharyngeal mucosa);
- Preparation of the patient for diagnostic manipulation in the nasal passages.
DOSING MODE
Intranasally.
Ximelin Eco 0.05% - spray for children from 2 to 10 years: 1 injection in each nasal passage; Do not use more than 3 times a day.
Ximelin Eco 0.1% - spray for adults and children over 10 years: 1 injection in each nasal passage (if necessary, repeat); Do not use more than 3 times a day.
The drug is applied no more than 10 days.
(one injection of Ximelin Eco 0.05% contains about 35 Ојg xylometazoline hydrochloride;
one Xymeline Eco injection 0.1% contains about 140 Ојg xylometazoline hydrochloride).
SIDE EFFECT
With frequent and / or prolonged use - irritation and / or dryness of the nasopharyngeal mucosa, burning, tingling, sneezing, hypersecretion.
Rarely - edema of the nasal mucosa, palpitations, tachycardia, arrhythmia, increased blood pressure, headache, vomiting, insomnia, impaired vision; depression (with prolonged use of high doses).
CONTRAINDICATIONS
- hypersensitivity to the components of the drug;
- arterial hypertension;
- tachycardia;
- severe atherosclerosis;
- glaucoma;
- Atrophic rhinitis;
- thyrotoxicosis;
- surgical interventions on the meninges (in the anamnesis);
- Pregnancy;
- Children's age under 2 years (for Ximelin Eko 0.05%); children under 10 years old (for Ximelin Eco 0.1%).
With caution: diabetes mellitus, angina pectoris III-IV functional class, prostatic hyperplasia.
During lactation, the drug should only be used after a thorough assessment of the benefit-risk ratio for the mother and the baby, do not exceed the recommended dosage.
PREGNANCY AND LACTATION
It is forbidden to take this medication during pregnancy.
During lactation, the drug should only be used after a thorough assessment of the benefit-risk ratio for the mother and the baby, do not exceed the recommended dosage.
APPLICATION FOR CHILDREN
Do not use the drug:
children's age to 2 years (for Ximelin Eko 0.05%);
children under 10 years old (for Ximelin Eco 0.1%).
SPECIAL INSTRUCTIONS
Do not use for a long time, for example, with chronic rhinitis.
OVERDOSE
Symptoms: increased side effects.
Treatment: symptomatic.
DRUG INTERACTION
Incompatible with monoamine oxidase inhibitors and tricyclic antidepressants.
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored at a temperature of no higher than 30 В° C. Keep out of the reach of children.
Shelf life - 3 years.
Do not use after the expiration date.
