Universal reference book for medicines
Product name: CODELAC В® BRONCHO with CABRETSOM (CODELAC BRONCHO with THYMUS SERPYLLUM)

Active substance: ambroxol, glycyrrhizinic acid, Serpylli herba

Type: The drug with mucolytic, expectorant and anti-inflammatory action

Manufacturer: Otisifarm (Russia) manufactured by FARMSTANDART-Lekssredstva (Russia)
Composition, form of production and packaging
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Elixir from light brown to brown; in the course of storage, the formation of a sediment is allowed.
5 ml

ambroxol hydrochloride 10 mg

sodium glycyrrhizinate 30 mg

liquid extract of thyme 500 mg

Auxiliary substances: methylparahydroxybenzoate (nipagin) - 3.75 mg, propyl parahydroxybenzoate (nipazol) - 1.25 mg, sorbitol (sorbitol) - 3000 mg, purified water - up to 5 ml.

50 ml - bottles of dark glass (1) complete with a measuring spoon - packs of cardboard.

100 ml - bottles of dark glass (1) complete with a measuring spoon - packs cardboard.

125 ml - bottles of dark glass (1) complete with a measuring spoon - packs cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2011.

PHARMACHOLOGIC EFFECT

Combined expectorant.
Has mucolytic and expectorant effect, and also has anti-inflammatory activity. The action of the elixir of CodelacВ® Broncho with thyme is due to the pharmacological properties of its components.
Ambroxol has secretory, secretory and expectorant action, normalizes the disturbed ratio of serous and mucous components of sputum, increases the secretion of surfactant in the alveoli.
Reduces the viscosity of sputum and promotes its spillage.
Sodium glycyrrhizinate has anti-inflammatory and antiviral effect.
Has a cytoprotective effect due to antioxidant and membrane-stabilizing activity. Strengthens the action of endogenous glucocorticoids, providing anti-inflammatory and anti-allergic effect. Due to its pronounced anti-inflammatory activity, it helps to reduce the inflammatory process in the respiratory tract.
Extract of herb thyme contains a mixture of essential oils, which have an expectorant and anti-inflammatory effect.
In addition, this extract has weak antispasmodic and reparative properties.
PHARMACOKINETICS

Data on the pharmacokinetics of the drug KodelakВ® Broncho with thyme are not provided.

INDICATIONS

Diseases of the respiratory tract with the formation of viscous sputum:

- Acute and chronic bronchitis;

- pneumonia;

- COPD;

bronchoectatic disease.

DOSING MODE

Is taken orally during a meal, with a little water.

Adults and children over 12 years - 10 ml 4 times / day.

Children aged 2 to 6 years are prescribed 2.5 ml 3 times / day, at the age of 6 to 12 years - 5 ml 3 times / day.

The maximum duration of treatment without a doctor's consultation is 5 days.

SIDE EFFECT

From the digestive system: rarely - diarrhea, dry mouth, constipation;
with prolonged use in high doses - gastralgia, nausea, vomiting.
On the part of the respiratory system: dryness of the mucous membrane of the respiratory tract, rhinorrhea.

Other: allergic reactions;
rarely - weakness, headache, dysuria, exanthema.
CONTRAINDICATIONS

- Pregnancy;

- the period of lactation (breastfeeding);

- Children under 2 years;

- Hypersensitivity to the components of the drug.

With caution should be used in patients with hepatic and / or renal insufficiency, peptic ulcer of the stomach and duodenum, bronchial asthma.

PREGNANCY AND LACTATION

Contraindicated use of the drug during pregnancy and lactation (breastfeeding).

APPLICATION FOR FUNCTIONS OF THE LIVER

Caution should be used in patients with renal insufficiency.

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

Caution should be used in patients with liver failure.

APPLICATION FOR CHILDREN

Contraindicated in children under 2 years.

SPECIAL INSTRUCTIONS

Do not combine with antitussive.

In patients with diabetes, it is possible to use the drug taking into account the content of sorbitol in the amount of 0.18 XE in 5 ml of elixir.

OVERDOSE

Symptoms: nausea, vomiting, diarrhea, indigestion.

Treatment: artificial vomiting, gastric lavage in the first 1-2 hours after taking the drug.

DRUG INTERACTION

Joint use with antitussive drugs leads to difficulty in sputum discharge.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children, protected from light at a temperature of no higher than 25 В° C.
Shelf life - 1.5 years.
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