Universal reference book for medicines
Product name: IODOXYD

Active substance: povidone-iodine

Type: Antiseptic for topical application in gynecology

Manufacturer: NIZHFARM (Russia)
Composition, form of production and packaging
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Suppositories of vaginal brown with a brownish hue of color, torpedo-shaped, marble surfaces are allowed.
1 supp.

povidone-iodine (iodine in the form of a complex of polyvinylpyrrolidone iodine) 200 mg

Excipients: polyethylene oxide 1500, polyethylene oxide 400.

5 pieces.
- packings cellular planimetric (2) - packs cardboard.
5 pieces.
- packings cellular planimetric (3) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2008.

PHARMACHOLOGIC EFFECT

Antiseptic for topical application in gynecology.
It blocks amino groups of cellular proteins. Has a wide spectrum of antimicrobial action.
It is active against bacteria (including Escherichia coli, Staphylococcus aureus), fungi, viruses, protozoa.

The active substance of the drug - iodine - is in the form of a complex with polyvinylpyrrolidone (povidone), referring to iodophors, which bind iodine.
The concentration of active iodine is 0.1-1%. Upon contact with the skin and mucous membranes, iodine is gradually and uniformly released, having a bactericidal effect on microorganisms. At the application site, a thin colored layer remains, which is retained until the entire amount of iodine is freed.
PHARMACOKINETICS

Data on the pharmacokinetics of the preparation Yodoxid are not provided.

INDICATIONS

- treatment of acute and chronic infectious-inflammatory diseases of the vagina (trichomonas, fungal, viral, nonspecific, mixed infections), bacterial vaginitis;

- prevention of infectious and inflammatory complications before gynecological interventions (artificial termination of pregnancy, installation and removal of the intrauterine device, diathermocoagulation of the cervix, hysterosalpingography).

DOSING MODE

In acute vaginitis - 1 suppository 2 times / day for 7 days, with subacute and chronic vaginitis - 1 suppository 1 time / day before bedtime for 14 days (regardless of the phase of the menstrual cycle).

The suppository is injected deep into the vagina in the supine position.

SIDE EFFECT

Allergic reactions: itching, hyperemia.

CONTRAINDICATIONS

- simultaneous therapy with radioactive iodine;

- herpetiform dermatitis of Dühring;

- Thyroid adenoma;

- thyrotoxicosis;

- newborns;

- Hypersensitivity to the components of the drug.

With caution should be used for chronic kidney failure.

PREGNANCY AND LACTATION

The use of the drug in the II and III trimesters of pregnancy is possible only if the perceived benefit to the mother exceeds the potential risk to the fetus.

Caution should be used during lactation.

APPLICATION FOR FUNCTIONS OF THE LIVER

With caution should be used for chronic kidney failure.

SPECIAL INSTRUCTIONS

In the presence of blood, the bactericidal action of the drug may decrease.

In the case of non-hypnotic hyperthyroidism and other diseases of the thyroid gland (especially in elderly patients) the drug is used only under strict indications and under constant medical supervision.

Avoid contact with eyes.

OVERDOSE

Data on the overdose of Yodoxide is not available.

DRUG INTERACTION

Iodine oxide is incompatible with disinfectants, preparations containing mercury, oxidants, alkalis and substances with acid reaction.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

List B. The drug should be stored in a dry, protected from light, out of reach of children at a temperature of no higher than 20 ° C.
Shelf life - 2 years.

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