Universal reference book for medicines
Product name: DOPPLELGERZ В® NERVOTONIK (DOPPELHERZ В®NERVOTONIK)

Active substance: Hyperici herba

Type: Phytopreparation with antidepressant activity

Manufacturer: QUEISSER PHARMA (Germany)
Composition, form of production and packaging
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Elixir in the form of a liquid of a reddish-brown color; During storage, a small deposit or clouding may form.
100 ml

liquid herb extract of St. John's wort 2.084 g

Excipients: cherry liqueur concentrate - 573 mg, liqueur wine - 101.543.

250 ml - bottles of dark glass (1) - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2013.

PHARMACHOLOGIC EFFECT

The preparation is of plant origin.
Has a sedative and antidepressant effect. The main active substances of St. John's wort have a positive effect on the functional state of the central and autonomic nervous system, which improves mood, increases mental and physical activity, normalizes sleep.
PHARMACOKINETICS

The action of the drug Doppelgerz В® Nervolotonics is the cumulative effect of its components, therefore it is not possible to carry out kinetic observations.

INDICATIONS

- psycho-vegetative disorders (accompanied by a decrease in mood, apathy, asthenia);

- anxiety and anxiety;

- neurotic reactions;

- Depressive states of mild and moderate severity.

DOSING MODE

The drug is taken orally 20 ml 3 times / day after meals and at bedtime regularly for 6-8 weeks.

If necessary, the appointment of repeated courses of application of the drug.

The patient should be warned about the need to see a doctor if there is no improvement after the treatment.

SIDE EFFECT

Rarely: dyspepsia, allergic reactions, photosensitization reactions (mainly in patients with fair skin).

CONTRAINDICATIONS

- severe depression;

- photosensitization at reception of preparations of a St. John's wort in the anamnesis;

- children's age till 12 years;

- Hypersensitivity to the drug.

With caution should prescribe the drug for liver disease, alcoholism, craniocerebral trauma, brain diseases.

PREGNANCY AND LACTATION

The drug is not recommended for use during pregnancy and lactation (breastfeeding).

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

With caution should prescribe the drug for liver disease.

APPLICATION FOR CHILDREN

Contraindicated in children under 12 years.

SPECIAL INSTRUCTIONS

Against the background of taking the drug, patients (especially with fair skin) should avoid prolonged exposure to the sun and UV irradiation (including visits to the solarium).

The preparation contains 18% by volume ethanol.
At observance of recommended dosages at each reception of a preparation in an organism 2.8 g of ethanol enter, in the maximum daily dose of a preparation contains 8.4 g of ethanol.
Impact on the ability to drive vehicles and manage mechanisms

During the period of taking the drug, one should refrain from carrying out potentially dangerous activities requiring increased attention and speed of psychomotor reactions (driving and other vehicles, working with moving mechanisms, dispatch and operator work).

OVERDOSE

Until now, there is no data on an overdose of St. John's wort preparations.
When taking the drug in a very high dose, it is possible to increase the side effects.
Treatment: cancellation of the preparation, reception of activated charcoal;
if necessary, medical monitoring of the patient's condition. Avoid exposure to sunlight for 1-2 weeks.
DRUG INTERACTION

The drug activates microsomal oxidation (cytochrome P450), so it should be used with caution when used with digoxin, theophylline, anticonvulsants, tricyclic antidepressants, selective serotonin reuptake inhibitors, migraine preparations (triptans), cyclosporine, indinavir, reserpine.

At simultaneous application the preparation can strengthen action of agents for the general anesthesia and opioid analgesics.

It is not recommended to take the drug simultaneously with MAO inhibitors.

Simultaneous reception with other photosensitizing agents may lead to increased photosensitivity.

The drug can be used with other psychotropic drugs.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children at a temperature of no higher than 25 В° C.
Shelf life - 3 years.
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