Universal reference book for medicines
Name of the drug: DEPANTOL ® (DEPANTHOL)

Active substance: chlorhexidine, dexpanthenol

Type: Preparation, improving trophic and tissue regeneration, with antimicrobial activity for external use

Manufacturer: NIZHFARM (Russia)
Composition, form of production and packaging
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Cream for external use in white or almost white.
1 g

dexpanthenol 52.5 mg

chlorhexidine bigluconate (in the form of 20% p-ra) 8.02 mg

Excipients: propylene glycol 100 mg, macrogol cetostearate (Eumulgin B2) 16 mg, cetostearyl alcohol (cetyl alcohol not more than 60%, stearyl alcohol not less than 40%) (Lanette O) 54 mg, liquid paraffin (vaseline medical oil) - 100 mg, vaseline - 100 mg, sodium hydrophosphate dodecahydrate - 0.2 mg, potassium dihydrogen phosphate - 7.8 mg, purified water - up to 1 g.

25 grams - tubes of aluminum (1) - packs of cardboard.

30 g - aluminum tubes (1) - cardboard packs.

50 g - aluminum tubes (1) - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

The product description was approved by the manufacturer for the 2009 print edition.

PHARMACHOLOGIC EFFECT

Combined drug, improving trophic and tissue regeneration, with antimicrobial activity for external use.

Dexpanthenol is a vitamin B of the body, it is metabolized into pantothenic acid, which is an integral part of coenzyme A and participates in the processes of acetylation, carbohydrate and fat metabolism, in the synthesis of acetylcholine, GCS, porphyrins.
Stimulates skin regeneration, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers. It has a regenerating, vitamin, metabolic and anti-inflammatory effect.
Chlorhexidine is an antimicrobial drug, an antiseptic.

It is active against Gram-positive and Gram-negative bacteria, incl.
Staphylococcus spp., Enterococcus spp., Pseudomonas aeruginosa, Escherichia coli, Streptococcus spp., As well as yeast-like fungi and dermatophytes .
Keeps activity in the presence of blood, pus, various secrets and organic substances.
Cream Depanthol protects the wound surface from infection, suppresses the course of the infectious process and accelerates healing.
PHARMACOKINETICS

Data on the pharmacokinetics of the drug are not available.

INDICATIONS

- treatment of wounds at risk of infection (including abrasions, cuts, scratches, cracks, scratching, insect bites, burns, trophic ulcers);

- treatment of postoperative wounds;

- treatment of infected wounds, burns (including sun rays), pressure sores, abrasions, cuts, cracks, trophic ulcers, diaper rash;

- treatment of infected dermatoses (including eczema and atopic dermatitis).

- diaper dermatitis, scratches with signs of infection in children;

- cracks and inflammation of the nipples of the mammary glands with signs of infection in nursing mothers.

DOSING MODE

The cream should be applied a thin layer on the affected area of ​​the skin 1 or several times / day according to the indications.

Breastfeeding mothers are recommended to lubricate the infected surface of the nipple after breastfeeding.

Breast children are applied to the infection site after changing clothes or water procedures.

SIDE EFFECT

Possible: allergic reactions.

CONTRAINDICATIONS

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

During pregnancy and during lactation, the use of the drug in large areas should be avoided.

APPLICATION FOR CHILDREN

Possible application for indications.

SPECIAL INSTRUCTIONS

Do not let the cream into the eyes.

OVERDOSE

Data on drug overdose are not provided.

DRUG INTERACTION

Chlorhexidine is incompatible with soap and other anionic substances.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

Keep out of the reach of children at a temperature of no higher than 25 ° C.
Shelf life - 2 years.
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