Universal reference book for medicines
Product name: DEXPANTENOL-HEMOFARM (DEXPANTHENOL-HEMOFARM)

Active substance: dexpanthenol

Type: Preparation, improving trophic and tissue regeneration, for external use

Manufacturer: HEMOFARM (Serbia)
Composition, form of production and packaging
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Ointment for external use 5% homogeneous, from white to light yellow color.
1 g

dexpanthenol 50 mg

Excipients: glycerol, petrolatum, lanolin, paraffin liquid, paraffin, stearyl alcohol, cetyl alcohol, water.

30 g - aluminum tubes (1) - cardboard packs.

INSTRUCTION FOR THE SPECIALIST.

The product description was approved by the manufacturer for the 2009 print edition.

PHARMACHOLOGIC EFFECT

Dexpanthenol is a derivative of pantothenic acid.
Dexpanthenol passes into the body in pantothenic acid, which is an integral part of coenzyme A and participates in the processes of acetylation, in the synthesis of acetylcholine, corticosteroids, porphyrins.
In addition, it takes part in virtually all metabolic processes (the cycle of tricarboxylic acids, the metabolism of carbohydrates, fats and fatty acids, phospholipids, proteins), stimulates the regeneration of the skin, mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers.
It has a regenerating, metabolic and weak anti-inflammatory effect.
PHARMACOKINETICS

When topical application is rapidly absorbed by the skin and converted to pantothenic acid, binds to plasma proteins (mainly with beta-globulin and albumin).
The concentration in the blood is 0.5-1 mg / l, in the blood serum - 100 μg / l. Pantothenic acid does not undergo metabolism in the body (except for inclusion in Ko-A), is excreted unchanged.
INDICATIONS

- dry skin;

- violation of the integrity of skin and soft tissues;

- minor damage;

- burns (thermal and solar);

- abrasions;

- bullous dermatitis;

- abscess;

- furuncle;

trophic ulcers of the lower leg;

- pressure sores;

- cracks;

- aseptic postoperative wounds;

- poorly engrafted skin grafts;

- treatment and prevention of cracks and inflammation of the nipples of the breast during lactation;

- nursing of infants;

- prevention and treatment of intertrigo;

- healing of the skin with minor damages;

- erythema from diapers in infants.

DOSING MODE

Outwardly.
For treatment of wounds, diaper rash, abscesses, bedsores, dermatitis, for breast care, infants - 5% ointment 2-3 times / day are applied to the affected surface with a thin layer and lightly rubbed according to the indication; on the area of ​​the nipple of the breast, ointment is applied as a compress after each breast-feeding.
Breast children Dexpanthenol is applied to the back, buttocks and inguinal area after each change of clothes or water procedure.

SIDE EFFECT

Perhaps the emergence of allergic reactions, if they appear, stop using the drug.

CONTRAINDICATIONS

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

Can be used during pregnancy and during lactation.

APPLICATION FOR CHILDREN

For the treatment of wounds, diaper rash, abscess, bedsores, dermatitis in infants - 5% ointment 2-3 times / day applied to the affected surface with a thin layer and lightly rub according to the indication.

Breast children Dexpanthenol is applied to the back, buttocks and inguinal area after each change of clothes or water procedure.

SPECIAL INSTRUCTIONS

Treatment of poorly healing skin grafts and trophic ulcers should be performed under the supervision of the attending physician.

Do not apply to dying wounds.

DRUG INTERACTION

Not identified.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

Store at temperatures between 15 ° and 25 ° C.
Keep out of the reach of children. Shelf life - 5 years.
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